Reversibility of the Chronic Post-Stroke State

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Forty patients with cerebral infarction associated with occlusion of the internal carotid artery (ICA) or the middle cerebral artery (MCA) were treated with hyperbaric oxygenation (HO). EEC analyses were performed regularly in order to assess the course of the cerebral lesion. Patients in an early post-stroke stage (III B) and patients in a chronic post-stroke stage (IV) had the changes in EEC analysis and neurological findings distributed evenly between these two groups.

In 27% of the cases, the improvement was considerable, 53% had moderate improvement, and 20% showed no change of condition. The improvement mainly consisted of an increase of alpha-wave and betawave activity over the affected brain region. We were able to show this fact clearly by means of the EEG-analj sis-system applied. The results show that (a) hyperbaric oxygenation therapy (HOT) has a very favorable influence upon the course of disease, and (b) simultaneous application of HOT and EEC analysis allows for a differentiation between reversible and irreversible post-stroke changes in brain tissue.

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