Endovenous Microwave Ablation of Varicose Veins: In Vitro, Live Swine Model, and Clinical Study

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AimThis study aims to investigate the application of the microwave generator to treat the patients with varicose veins.Materials and MethodsPhase 1: Explanted saphenous veins in subcutaneous layer of the pork meat were ablated at 0, 40, 50, 60, and 70 W. Phase 2: The forelimb veins and the hindlimb arteries of a 40-kg swine were ablated at 50 and 60 W. Phase 3: The patients were treated with endovenous microwave ablation at 50 W.ResultsPhase 1: Perivenous tissue injury was found in groups 50, 60, and 70 W. Phase 2: Less perivenous tissue injury was found in group 50 W. Phase 3: Complete venous occlusion rate was 65% and venous reflux-free was 85% in 1 year. No severe complication was found.ConclusionsThe microwave generator with 50-W power setting could be used to ablate the varicose veins safely.

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