Although a number of innovative and futuristic operating room (OR) designs have been proposed, the challenge to implement the OR of the future has never been fulfilled. We believe the setting of future OR should be an integration of the entire spectrum of surgical care: from diagnostic to preoperative planning, and from intraoperative navigation to education. Besides overcoming the deficiencies of today's OR, it should also create a platform that allows easy inclusion of upcoming innovation. The opening of the brand new, innovative operating room in the Pamela Youde Nethersole Eastern Hospital, the Endo-Lap OR, is considered a benchmark in the territory. As minimally invasive surgery continues to flourish, we believe the concept and vision behind this Endo-Lap OR will help to shed light on the future development of OR.