New HLA-B alleles detected by polymerase chain reaction–sequence-specific oligonucleotide typing: HLA-B*0725, B*0728, and B*3808

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Abstract

Three novel alleles, human leukocyte antigen (HLA)-B*0725, B*0728, and B*3808, were discovered during routine genotyping of samples for the Australian Bone Marrow Donor Registry and Australian Cord Blood Bank. The new alleles contain amino acid changes in the antigen-binding site of the expressed HLA protein, which may alter the antigen-binding properties of the functional protein.

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