HLA-A*3318, a novel allele, identified by sequence-based typing in a Chinese individual

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Abstract

We report a novel human leucocyte antigen (HLA)-A allele, officially named as A*3318, which was found during high-resolution sequence-based typing in a Chinese potential hematopoietic stem cell transplantation donor. Compared with the HLA-A*330301 sequence, the A*3318 has one nucleotide substitution in exon 3: at nt 413 where A→G resulting in an amino acid substitution from Q (CAG) to R (CGG) at codon 114.

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