Sequencing of four new HLA-C alleles, Cw*070403, Cw*0757, Cw*1705, and Cw*0223

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Abstract

Sequencing-based typing for unrelated hematopoietic stem cell transplantation studies rendered four new HLA-C alleles. HLA-Cw*0757, Cw*070403, and Cw*1705 differ by single point mutations from their most similar alleles, Cw*070105, Cw*070401, and Cw*1701, respectively. In contrast, Cw*0223 discloses five amino acid replacements at the α2 domain regarding Cw*020202.

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