Design rationale, surgical technique, and soft tissue manipulation weigh heavily on the kinematic performance of total knee arthroplasty. As the orthopedic community continues its quest to provide more functional total knees, one must consider the importance of kinematics. Various investigations involving in vivo, in vitro, and computational methodologies have led to a sound understanding of normal knee kinematics. The results of such investigations are used in the development of new total knee arthroplasty designs and surgical technique. With years of research and development the question remains, “Do TKAs enable normal knee kinematics?” This work reviews results from published fluoroscopic research and presents new data to shed light on this question.