Chondral injuries of the knee are commonly seen at arthroscopy, yet there is no consensus on the most appropriate treatment method. Untreated cartilage injury predisposes to osteoarthritis, contributing to pain and disability. New synthetic polymer scaffolds in cartilage repair have been developed, which may allow early mobilization and optimize functional results while minimizing treatment downtime and multistep surgery. Indications for use and tips to access all areas of the knee are not widely available. This paper details the surgical technique for implantation of synthetic osteochondral plugs in the knee (TruFit; Smith & Nephew, London, United Kingdom) and outlines valuable tips in accessing the articular areas and achieving a new flush articular surface.