Isolated fractures of the greater tuberosity (GT) are common. Both cadaveric and clinical studies have indicated that only 5 mm of displacement can lead to poor functional outcomes secondary to rotator cuff imbalance and subacromial impingement. Multiple techniques have been described for operative fixation of isolated GT fractures; however, inherent problems exist with each technique. The purpose of this study is to describe a novel open surgical technique for isolated GT fractures that combines cancellous screw and suture anchor fixation. The benefits include a complimentary biomechanical construct that provides rigid fixation in both comminuted and noncomminuted fracture patterns to allow early rehabilitation while minimizing hardware failure and subsequent malunion.