Biological Augmentation of Rotator Cuff Repair: Platelet-rich Plasma (PRP) and Bone Marrow Aspirate (BMA)

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Biological therapies that can augment tendon to bone healing are desirable for the management of clinical conditions such as failed rotator cuff (RC) repair, chronic retracted RC tears, and RC tears in a compromised host (smokers, chronic medical conditions including diabetes). Bone marrow aspirate and platelet-rich plasma are 2 autologous biological therapies that are currently being used clinically to augment tendon to bone healing. The indications for this biological therapy, its efficacy, duration, dosage, and optimum cellular concentration are in the process of evolution and require continued ongoing investigations for further optimization. In this technique article, we describe the biological basis and our technique for the preparation and use of platelet-rich plasma and bone marrow aspirate for augmentation of RC repair.

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