Trazodone toxicity: Current concepts

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Abstract

Trazodone is a commonly prescribed antidepressant medication that is frequently encountered in drug overdoses. All too often, emergency physicians are uncertain how to treat patients who have ingested trazodone. Unfortunately, this uncertainty leads to both patient under treatment and over treatment. This article discusses trazodone pharmacology and toxicology and presents management principles that will allow emergency physicians to appropriately treat patients with trazodone ingestions.

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