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Mechanical bridging to cardiac transplantation with a ventricular assist device may be a life-saving procedure for patients with end-stage heart failure. Here we report our 3 cases of patients implanted with the MicroMed DeBakey VA® (ventricular assist device). Three male patients, aged 37, 41, and 40, had end-stage left heart failure due to idiopathic cardiomyopathy and were listed for cardiac transplantation. They had progressive hemodynamic deterioration. Although Patient 1 underwent surgery, after device implantation, for bowel necrosis caused by thromboemboli of unknown origin, heart transplantation was performed 70 days after implantation. Pump thrombosis occurred in Patient 2 on the 120th day. Outflow graft ligation was performed because the patient refused a pump exchange. This patient died on the 25th day after ligation and the 145th day after ventricular assist device implantation. A heparin-coated version of the device was implanted in Patient 3, whose preoperative profound biventricular failure had been improved by inotropic medication and intra-aortic balloon pump support. Successful heart transplantation was performed 161 days after implantation.