Cognitive Aging and Changes in Brain Morphology: A Narrative Review

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Abstract

Cognitive aging can produce morphological brain changes that contribute to cognitive impairments different from the neuropathological presentation of disease. To understand age-related changes to human cognition, it is important to recognize normal morphological changes that occur within the aging brain. The purpose of this narrative review is to familiarize the reader with current concepts in neurocognitive aging, summarize current evidence regarding structural and functional connectivity changes, and briefly discuss a relationship between the aging brain, morphological changes, and cerebral hemodynamics.

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