Editorial
Immunophilin Receptors for Immunosuppressive Drugs
Quality Assurance Programs for Immunosuppressive Drugs
Therapeutic Monitoring of Rapamycin
The Use of Concentration Measurements of Parent Drug and Metabolites During Clinical Trials
Area-Under-the-Curve Versus Trough Level Monitoring of Cyclosporine Concentration
Alternative Approaches for Phase I Studies of Anticancer Drugs
Dose-Response and Concentration—Response Relationships
The Development of a Bedside Algorithm Capable of Targeting Anti-Endotoxins to the Responder Subpopulations
Computer-Guided Concentration-Controlled Trials in Autoimmune Disorders
Biotechnology
Antifolate Analogs
Relating Blood Concentrations of Tetrahydrocannabinol and Metabolites to Pharmacologic Effects and Time of Marijuana Usage
Cocaethylene
Acute Tolerance to Pressor Effects of Cocaine in Humans
Response of the Newborn Cerebral Circulation to Cocaine
Tissue Plasminogen Activator (t-PA)
Recent Advances in High-Performance Liquid Chromatography/Mass Spectrometry and High-Performance Liquid Chromatography/Tandem Mass Spectrometry
Gas Chromatography/Tandem Mass Spectrometry Measurement of Δ9-Tetrahydrocannabinol, Naltrexone, and Their Active Metabolites in Plasma
Mass Spectrometric Investigations of Drug-Receptor Interactions
Stereoselective Separations of Chiral Anticancer Drugs and Their Application to Pharmacodynamic and Pharmacokinetic Studies
Advances in Chromatography for Clinical Drug Analysis
Assessment of Supercritical Fluids for Drug Analysis
Aluminum Neurotoxicity in Experimental Animals
Aluminum Toxicity in Patients with Chronic Renal Failure
The Chemistry of Desferrioxamine Chelation for Aluminum Overload in Renal Dialysis Patients
Desferrioxamine and Alzheimer's Disease
Use of Therapeutic Drug Monitoring in Pharmacoeconomics
Announcements
Subject Index
Author Index