T1 Rev-erbα, a novel anti-inflammatory target, modifies the circadian oscillation of pulmonary inflammation
T2 Blockade of intraalveolar p55 TNF-receptor signalling by a domain antibody decreases inflammation and oedema in an in vivo mouse model of ventilator-induced lung injury
T3 Tissue inhibitor of metalloproteinase-3 (TIMP3) protects against inflammatory processes in Interstitial Lung Disease (ILD)
T4 Increased reticular basement membrane thickness but NOT airway smooth muscle in endobronchial biopsies of severe preschool wheezers
T5 KCa3.1 ion channel blockers restore corticosteroid sensitivity in cytokine-treated airway smooth muscle (ASM) cells from both COPD and asthmatic patients
T6 Acute exacerbations of chronic obstructive pulmonary disease
S1 HIV-1 infection of macrophages modulates host responses to Mycobacterium tuberculosis to contribute to immunopathogenesis and viral propagation
S2 Multi-drug Resistant Tuberculosis (MDR-TB) treatment in the UK
S3 Factors for successful treatment completion among MDR TB cases in the UK
S4 Evaluation of TB peer educators—essential partners in metropolitan TB control
S5 Prevalence of latent tuberculosis infection in immigrants to the UK
S6 Sensitivity and specificity of mobile digital chest radiography for the diagnosis of active pulmonary tuberculosis. A cohort study in high risk groups in London
S7 Annual trends in asthma emergency attendance, hospital admission and readmission
S8 The National COPD Resources and Outcomes Project (NCROP)
S9 Feasibility of establishing a Regional Weaning Unit in Scotland
S10 Is it cost-effective to replace nurses with lay asthma educators in primary care?
S11 The South East Essex (SEE) model of integrated COPD care and QUIP (Quality Innovation and Productivity) improvements
S12 Pre-clinic telephone consultations
S13 The primary results of the MOSAIC trial
S14 CPAP improves endothelial function in minimally symptomatic OSA patients
S15 An office based advanced driving simulator to assess driving performance in Obstructive Sleep Apnoea Syndrome (OSAS)
S16 Detection of sleep-disordered breathing in chronic heart failure patients
S17 A pilot study of the prevalence of sleep disordered breathing (SDB) and nocturnal hypoxia in symptomatic adults with Sickle Cell Disease (SCD) and its relationship with disease severity
S18 Longitudinal assessment of biomarkers for clinical trials of novel therapeutic agents
S19 Real time PCR in the identification and management of Aspergillus in CF
S20 The bacterial cytoskeleton—a new antimicrobial target in cystic fibrosis pathogens?
S21 Identification of Pseudomonas aeruginosa infection via volatile organic compounds in sputum headspace gases
S22 Lung clearance index, FEV1 and CT findings in cystic fibrosis
S23 A comparative study of polymicrobial diversity in CF and non-CF bronchiectasis
S24 Differentiated primary bronchial epithelial cell (pBECs), monocyte derived macrophages (MdMs) and monocyte derived dendritic cells (MODCs) transwell co-culture
S25 IL 17 production in primary and secondary Respiratory Syncytial Virus (RSV) infection and neutrophil transmigration
S26 Recurrent respiratory tract infections and specific antibody deficiency in children
S27 Should routine screening for vitamin d deficiency be incorporated into current guidelines for treatment of paediatric TB patients?
S28 Clinical predictors of admission in infants with acute bronchiolitis
S29 Mannose binding lectin deficiency in children with respiratory infection
S30 TRUSS is a regulator of TNFα-TNF-R1 induced NF-κB activation
S31 Characterisation of cell adhesion molecule-1 in lung mast cells
S32 Cyclical mechanical stretch enhances the pro-fibrotic responses of primary embryonic foetal fibroblasts, but not ADAM33 expression
S33 Suppression of constitutive and stimulated secretion of histamine from human lung mast cells by a secreted factor from lung epithelial cells
S34 Effects of the cyclin-dependent kinase inhibitor R-roscovitine on eosinophil survival and clearance
S35 A randomised controlled trial comparing combined EBUS/EUS followed by surgical staging versus surgical staging alone in non-small cell lung cancer
S36 Check novel in vivo real time imaging of the bronchial mucosa using an endo-cytoscopy
S37 Comparison of dynamic contrast enhanced MRI (DCE-MRI) parameters with integrated PET-CT and serum mesothelin in the baseline assessment of malignant pleural mesothelioma
S38 Fourier transform infra-red (FTIR) spectroscopy on sputum from lung cancer patients, healthy controls and a high-risk cohort
S39 Sub typing of non small cell carcinoma in EBUS-TBNA samples
S40 Early experience of endobronchial ultrasound-miniprobe (EBUS-MP) for investigation of peripheral pulmonary mass lesions
S41 Expression of functional receptor activity modifying protein (RAMP)-1 by airway epithelial cells with dysregulation in asthma
S42 Airway epithelial toll receptor expression in asthma and its relationship to disease severity
S43 The expression of CRACM ion channels in human lung mast cells
S44 Increased expression of immunoreactive thymic stromal lymphopoetin in severe asthma
S45 Functional KCa3.1 K+ channels are required for human fibrocyte migration
S46 Activation of TGF-β by airway smooth muscle cells via the αVβ5 integrin in asthmatic airway remodelling
S47 RAGE-mediated cytokine release from leukocytes
S48 NGAL inhibits cytoskeletal re-organisation, MMP-2 production and invasion in alveolar epithelial cells in an in vitro model of acute lung injury
S49 Is the development of acute lung injury influenced by increased levels of IL17 as a result of Treg/TH17 imbalance?
S50 Evaluation of secretory leucoprotease inhibitor (SLPI) as an anti-inflammatory therapy for donor lung inflammation
S51 Thioredoxin modifies MIF release from human monocytes following stimulation with LTA and LPS
S52 The role of the Receptor for Advanced End Products (RAGE) in Acute Lung Injury (ALI)
S53 Nanoparticles cause pulmonary inflammation through IL-1α and partial activation of the NLRP3 inflammasome
S54 Characterising sarcoidosis using a web-based registry
S55 Pulmonary fibrosis with and without co-existing connective tissue disease
S56 Flat Trachea Syndrome
S59 Aα-Val360
S57 Evaluation of circulating biomarkers in lymphangioleiomyomatosis
S58 Pulmonary Langerhans’ Cell Histiocytosis (PLCH)
S60 Cigarette smoke induced oxidation of α-1 antitrypsin amplifies the pulmonary inflammatory response
S61 Cigarette smoke promotes polymerisation of Z α1-antitrypsin
S62 Characterisation of a novel “pseudo-Z” variant of α1-antitrypsin
S63 Use of NMR spectroscopy and nanospray mass spectrometry to characterise binding of lead compounds for drug design in α1-antitrypsin deficiency
S64 Changes in physiological phenotypes of α-1-antitrypsin deficiency with time
S65 Interim data from a randomised controlled trial of average volume-assured pressure support (AVAPS) versus spontaneous-timed (ST) pressure support in Obesity Hypoventilation Syndrome (OHS)
S66 A randomised crossover trial of pressure support ventilation (PSV) versus pressure controlled ventilation (PCV) in stable hypercapnic Chronic Obstructive Pulmonary Disease (COPD)
S67 Phenotypic differences between obese patients with eucapnic and hypercapnic sleep-disordered breathing (SDB)
S68 Evaluation of non-invasive ventilation in management of acute severe asthma
S70 Non-invasive ventilation (NIV) in Chronic Obstructive Pulmonary Disease (COPD) exacerbations with acute hypercapnic respiratory failure (AHRF) with pH
S71 Ambulatory oxygen improves the effectiveness of Pulmonary Rehabilitation (PR) in selected patients
S72 The utility of the modified BODE index (incorporating the incremental shuttle walking test) in assessing survival in patients with COPD screened for Pulmonary Rehabilitation (PR)
S73 4-Metre gait speed as a functional outcome measure in patients with Chronic Obstructive Pulmonary Disease (COPD)
S74 Effect of pulmonary rehabilitation on the Short Physical Performance Battery (SPPB) in COPD
S75 Is a practice incremental shuttle walk test always necessary and is it influenced by MRC dyspnoea grade?
S76 The COPD assessment test score (CAT)
S77 Compartmentalisation of surface Triggering Receptor Expressed on Myeloid Cells-1 (TREM-1) in Ventilator-Associated Pneumonia (VAP)
S78 Determinants of macrophage responses to Streptococcus pneumoniae
S79 Potential diagnostic significance of neutrophil proteases in ventilator-associated pneumonia
S80 The role of MyD88 in rhinovirus 1B infection
S81 Primary type II alveolar epithelial cells respond differentially to bacterial virulence factors
S82 Survival of HIV-infected patients admitted to the intensive care unit
S83 Preschool wheezing phenotypes in a representative UK birth cohort
S84 Childhood incident asthma and physical activity
S85 The effects of exposure to IL-9 alone or in combination with IL-13 on the mucociliary differentiation of bronchial epithelial cells from normal and asthmatic children.
S86 Effects of exposure to IL-13, IL-31 and an IL-13/31 combination on mucociliary differentiation of bronchial epithelial cells from normal children
S87 Relationship between bronchial reticular basement membrane thickness (RBM) and smooth muscle mass in childhood severe asthma (SA)
S88 Mast cell myositis is associated with persistent airflow limitation (PAL) in childhood severe asthma (SA)
S89 Bimodal iron oxide nanoparticles for hyperthermia therapy and MR imaging in cancer
S90 Homocystine levels in non-small cell lung cancer
S91 The role of the vitamin D axis in lung cancer
S92 Epithelial mesenchymal transition occurs earlier than previously thought in the development of squamous cell carcinoma of the lung
S93 Is Bcl-2 important in small cell lung cancer?
S94 Two novel determinants of etoposide resistance in small cell lung cancer
S95 Application of proteomics to explore the pathobiology of pulmonary arterial hypertension
S96 Novel biomarkers in idiopathic pulmonary arterial hypertension
S97 Inflammatory cytokines are elevated in patients with operable chronic thromboembolic pulmonary hypertension and predict outcome post-endarterectomy
S98 Ventilatory efficiency in pulmonary arterial hypertension and chronic thromboembolic pulmonary hypertension
S99 Multiple regression analyses in a cohort of hereditary haemorrhagic telangiectasia patients suggest a novel role for iron in thrombosis
S100 Change in diastolic pulmonary artery pressure (3 months post surgery compared to pre-surgery value) as a long-term prognostic parameter in patients treated with pulmonary endarterectomy for chronic thromboembolic pulmonary hypertension
S101 Praziquantel prevents progression and reverses pulmonary hypertension and pulmonary vascular remodelling in a mouse model of Schistosomiasis
S102 KGF enhances pulmonary production of pro-epithelial repair factors in a human in vivo model of acute lung injury
S103 A decrease in elafin due to proteolytic cleavage may contribute to alveolar inflammation in patients with ALI
S104 Monocyte influx accompanies the early neutrophilic inflammation seen in bronchoalveolar lavage fluid following lipopolysaccharide inhalation
S105 Does vitamin D deficiency increase risk of acute lung injury post oesophagectomy?
S106 Polymorphisms in genes encoding RAGE or RAGE ligands predispose patients to adverse outcomes following surgery necessitating cardiopulmonary bypass
S107 Comparison of high-stretch versus atelectasis in the pathophysiology of ventilator-induced lung injury using the mouse isolated perfused lung
S109 Current COPD care in the UK; results from 180 000 patients in the POINTS database
S108 A historical cohort study to determine the prevalence of common chronic respiratory diseases and medication use in drug misusers
S110 Employment histories of people with asthma in the 1958 birth cohort
S111 Asthma, puberty and BMI in the 1958 British Birth Cohort
S112 The natural history of wheeze from birth to adult life
S113 The effect of small airways disease and emphysema on the association between smoking and lung function, and bronchodilator response
S114 A double blind, placebo controlled, randomised, study to assess the effects of placebo, codeine and Talnetant, on citric acid cough threshold in healthy subjects
S115 Magnitude of cough response to inhaled capsaicin differentiates between health and disease
S116 Urge-to-cough intensity in chronic cough patients compared to asthmatics and healthy controls
S117 4 h cough frequency monitoring with the Leicester Cough Monitor
S118 Acute hemispheric stroke patients have reduced functional residual capacity and cough flow rates
S119 Variation in pharyngeal pH in the diagnosis of airway reflux
S120 IL-1 is a key epithelial alarmin which promotes fibroblast activation
S121 Individual cell tracking in a transgenic zebrafish inflammation model reveals the fates of inflammatory neutrophils during inflammation resolution
S122 The M1 macrophage phenotype accentuates TGF-β1 driven epithelial to mesenchymal transition (EMT) via the secretion of TNFα
S123 Mononuclear inflammation and disruption of normal alveolar structure following deletion of Gαq/11, but not Gα12/13, in type II alveolar epithelial cells
S124 Macrophage deletion of vHL results in alternative activation and enhanced lung fibrosis independent of HIF-1
S125 Ly6Chi circulating monocytes direct alternatively activated, pro-fibrotic, lung macrophage regulation of pulmonary fibrosis
S126 Measuring quality in pneumonia care. The north west advancing quality programme 2008–2009
S127 Is healthcare associated pneumonia a distinct clinical phenotype?
S128 Analysis of volatile biomarkers within exhaled breath for the diagnosis of pneumonia
S129 Predicting outcome from HIV-associated pneumocystis pneumonia
S130 Outcomes of pseudomonas eradication therapy in patients with non-cystic fibrosis bronchiectasis
S131 Fatigue in bronchiectasis
S132 Airway dysfunction and inflammation in pool and non-pool based elite endurance athletes
S133 Eosinophilic airway inflammation is associated with FEV1 decline in severe asthma
S135 Can your mobile phone improve your asthma?
S136 Fungal sputum culture in patients with severe asthma is associated with a reduced post bronchodilator FEV1
S137 The At-Risk Registers in Severe Asthma (ARRISA) Study
S138 Clara cells inhibit alveolar epithelial wound repair through a TRAIL-dependent apoptosis mechanism
S139 The K+ channel KCa3.1 is a novel target for the treatment of idiopathic pulmonary fibrosis
S140 The role of transforming growth factor-β activated kinase-1 (TAK-1) in the development of airway fibrosis
S141 A disintegrin and metalloprotease (ADAM) 33 protein in patients with pulmonary sarcoidosis
S142 The K+ channel KCa3.1 is expressed in human lung fibroblasts
S143 Serum mannose binding lectin deficiency is present in patients with early onset interstitial pulmonary fibrosis and those with affected relatives suggesting a genetic risk factor for defects in the innate immune system
S144 Cigarette smoke dysregulates pro-inflammatory cytokine release from airway epithelial cells and macrophages in response to haemophilus influenzae
S145 The impact of cigarette smoke extract on inflammatory responses and toll-like receptor-4 expression in healthy nasal epithelial cells
S146 Microvascular endothelial cell apoptosis and dysregulation of Vascular Endothelial Growth Factor Receptor 2 (VEGF-R2) in response to cigarette smoke. New insights into the pathogenesis of emphysema
S147 Diesel exhaust particles alter monocyte differentiation in vitro but have little impact on neutrophil function
S148 Regulation of neutrophil apoptosis by phosphoinositide 3-kinases
S149 Characterisation of T cell populations in the lung
S150 Smad-dependent and Smad-independent induction of Id1 by prostacyclin analogues inhibits proliferation of pulmonary artery smooth muscle cells in vitro and in vivo
S151 TRAIL deficiency is protective in experimental pulmonary arterial hypertension
S152 Dexamethasone reverses established monocrotaline-induced pulmonary hypertension in rats and increases pulmonary BMPR2 expression
S153 Bone morphogenetic protein receptor-II regulates pulmonary artery endothelial cell barrier function
S154 Is there a role for IL-33 in the pathogenesis of pulmonary arterial hypertension?
S155 The role of ST2 in a model of pulmonary hypertension
S156 Chloride intracellular channel protein 4 (CLIC4) in the regulation of human pulmonary endothelial responses to hypoxia
S157 Prevalence of asthma related to employment in the UK
S159 Do occupational asthmatics with small changes in PEF at work have less FEV1 decline than those with larger changes?
S160 The effect of shift work on serial peak expiratory flow measurements used to diagnose occupational asthma
S158 Occupational asthma; referral patterns from primary care in the UK
S161 Reducing exposure to allergens in bakeries
S162 Job categories and risk of adult onset asthma in the 1958 birth cohort from age 16 to age 42 years
S163 The ‘Obesity Paradox’ in chronic obstructive pulmonary disease
S164 Diminished left ventricular end-diastolic dimensions predict an amplified risk of death in chronic obstructive pulmonary disease
S165 Deprivation is an independent predictor of 1-year mortality in outpatients with chronic obstructive pulmonary disease
S166 The role of clinical, metabolic and cardiac biomarkers in predicting outcome from COPD exacerbations requiring hospital admission
S167 Expansion of the red cell distribution width and evolving iron deficiency as predictors of poor outcome in chronic obstructive pulmonary disease
S168 Evaluation of the MRC dyspnoea scale and a novel extended version in prediction of in-hospital death and early readmission in acute exacerbations of COPD
P1 Quality of life related to COPD and occupational exposures
P2 Outbreak case definitions for extrinsic allergic alveolitis due to metalworking fluids
P3 COPD causation; an assessment of agreement between expert clinical raters
P4 Breathlessness and work performance in older adults in Kent
P5 Airway responsiveness measurements in asthmatic recruits to emergency services
P6 Work-related respiratory symptoms in the UK; Do primary care physicians miss diagnostic opportunities in occupational asthma?
P7 Occupational eosinophilic constrictive bronchiolitis with asthma in a foam cutter caused by Soya bean products
P8 Unique outbreak of occupational asthma in toolmakers caused by chrome
P9 The evaluation of an improved method of occupational asthma diagnosis from timepoint analysis of serial PEF records
P10 Asbestos-induced diffuse pleural thickening—a continuing problem
P11 Cardio-respiratory fitness at work; the effects of public health guidance?
P12 Alarming ignorance about the dangers of asbestos among UK homeowners
P13 Clinical, radiographic and pulmonary function findings in silicosis
P14 Does Vitamin D Axis have an effect on the severity of Asthma?
P15 Concerns about corticosteroids among people with asthma
P16 Fluticasone propionate/formoterol fumarate combination therapy has an efficacy and safety profile similar to that of its individual components administered concurrently
P17 Self-reported physical activity levels and attitudes towards a structured exercise programme in adults with difficult asthma
P18 Experimental infection with low dose rhinovirus in asthma
P19 Psychosical factors and the morbidity of severe asthma
P20 The eligibility of patients with difficult asthma for omalizumab since the change to the treatment criteria
P21 Success rate of sputum induction in the Leicester paediatric severe asthma clinic using
P22 Factors associated with refractoriness to repeat exercise challenge in adults with asthma
P23 Effect of omalizumab on oral corticosteroid requirements of young children with severe asthma; results of a UK survey
P24 Fluticasone propionate/formoterol fumarate combination therapy has a more rapid onset of action than fluticasone propionate/salmeterol xinafoate in the treatment of asthma
P25 Relationships between airway hyper-responsiveness, airway inflammation and airway calibre in asthmatic subjects
P26 Home serial spirometry as an adjunct in the diagnosis of vocal cord dysfunction
P27 Personal allergen exposures are increased by changes in sleep position and improved by temperature-controlled laminar airflow
P28 Inflammatory profiling of adventitial fibroblasts in pulmonary hypertension
P29 Endothelial cell NF-kB activation is increased in human idiopathic PAH
P30 The changing face of pulmonary hypertension
P31 Disease targeted therapies and effect on survival in idiopathic, heritable and anorexigen-associated pulmonary arterial hypertension (PAH)
P32 Delivering pulmonary hypertension services—5 year experience from a Satellite centre
P33 Iron deficiency independently predicts survival in idiopathic pulmonary arterial hypertension
P34 Characterising T cell sub-populations in pulmonary hypertension
P35 Elevated tricuspid regurgitation jet velocity on echocardiogram in Sickle Cell Disease is associated with raised inflammatory mediators and low steady state haemoglobin but not other markers of haemolysis
P36 Functional class and gas transfer are useful tools in the assessment of pulmonary hypertension associated with sickle cell disease
P37 Flying—safer than we thought? A questionnaire-based study of 156 individuals with hereditary haemorrhagic telangiectasia; 95 with pulmonary AVMs
P38 Which patients with pulmonary arteriovenous malformations are dyspnoeic? Retrospective analysis of a single centre 2005–2010 cohort
P39 Pulmonary Hypertension (PH) associated with lung disease/ hypoxia
P40 A comparison of the value of oxygen shunt studies and cardiac bubble echo as screening tools for pulmonary arteriovenous malformations in patients with suspected hereditary haemorrhagic telangiectasia
P41 The COPD Assessment Test (CAT) used to evaluate outcome in pulmonary rehabilitation
P42 Comparison of a 1- and 2-walk protocol for the endurance shuttle walk test when measuring change due to therapeutic intervention in COPD patients
P43 Do changes in objective outcome measures match patient-reported experience of pulmonary rehabilitation?
P44 COPD Patients derived benefits from attending PR
P45 Outcomes following pulmonary rehabilitation for patients with restrictive lung diseases with or without oxygen therapy
P46 Effects of physical activity top up ‘PAT on the back’ programme on exercise capacity and healthcare utilisation for people with chronic obstructive pulmonary disease (COPD)
P47 Outcomes of static vs continuous rolling community pulmonary rehabilitation (PR) programmes
P48 Attendance rates and response to pulmonary rehabilitation
P49 Seasonal effect upon attendance at a pulmonary rehabilitation programme
P50 Facilitation of continued exercise via patient volunteers with chronic obstructive pulmonary disease (COPD) following a pulmonary rehabilitation programme
P51 Group-based pulmonary rehabilitation delivered to the home via the internet—a feasibility study
P52 Is a pulmonary rehabilitation (PR) programme effective in reducing severe symptoms of anxiety and depression in patients with COPD?
P53 The Effect of co-morbidities on response to pulmonary rehabilitation
P54 Do the NICE new entrant TB screening guidelines under-diagnose cases of latent TB infection?
P55 Post-bronchoscopy sputum
P56 High incidence of tuberculosis in patients with chronic kidney disease in a tertiary referral unit
P57 The London TB Metrics
P59 Why do we often fail to meet the gold standard for the diagnosis of active tuberculosis?
P58 What does pulmonary tuberculosis (TB) look like in London?
P60 Questionable utility of T-SPOT testing in a TB exposure incident on a Clinical Haematology Unit
P61 Pulmonary nontuberculous mycobacterial (NTM) culture is common following lung transplantation, and NTM lung disease is associated with poor prognosis
P62 Are we missing opportunities to obtain a microbiological diagnosis of TB?
P63 A prospective observational trial examining the diagnostic utility of serum and pleural fluid procalcitonin in the initial investigation of unilateral pleural effusions
P64 Course and variation of the intercostal artery by computed tomography
P65 Is serum N-terminal pro B type natriuretic peptide (NT-proBNP) measurement useful in the investigation of unilateral pleural effusions?—a prospective observational study
P66 Histone deacetylase inhibitor CBHA attenuates the expression of plasminogen activator inhibitor-1 in human pleural mesothelial cells
P67 Outcomes from surgical management of pleural infection
P68 Surgery for mesothelioma
P69 Mesothelioma in the 21st century. A 1-year survey of malignant mesothelioma in the South West of the UK
P70 Talc slurry pleurodesis
P71 Reduced airway beta-defensin 2 levels in children with cystic fibrosis and vitamin D-deficiency
P72 Feasibility of recruiting newborn babies with cystic fibrosis diagnosed by newborn screening to a clinical study with invasive outcome measures
P73 The complexities of defining atopy in severe childhood asthma
P74 British asthma guideline revision does affect prescribing patterns in children
P75 Clinical predictors of continuous positive airway pressure requirement in bronchiolitis
P76 General and respiratory health outcomes in adult survivors of bronchopulmonary dysplasia
P77 Children's exposure to airborne fine particulate matter at home and asthma outcomes
P78 Impact of severe allergic asthma in children
P79 Impulse oscillometry for the assessment of lung function deficits associated with preschool wheezing
P80 Pre-operative assessment of children undergoing scoliosis surgery
P81 The changing incidence of paediatric empyema in NE England 2006–2010
P82 What is the role of chest computed tomography in children with parapneumonic effusion?
P83 Validation of a novel Porcine–Resin thorax model for Chest drain insertion training
P84 The impact of a multidisciplinary educational programme on the prescribing of oxygen in an acute trust
P85 Pictorial representation of respiratory examination in hospital notes
P86 Chest Drain insertion training; is Simulation training the answer?
P87 Evidence-based emergency oxygen guidelines are not being followed in the emergency department
P88 The Aintree Hospital Pleural Disease Training Programme
P89 A decade on still not enough time for asthma
P90 Simulated bronchoscopy training delivered by experienced peers improves confidence of new trainees
P91 Can healthcare professionals in a respiratory unit correctly set an oxygen flow rate on a standard oxylitre medical regulator?
P92 Training opportunities in thoracic ultrasound for respiratory specialist trainees in the West Midlands Deanery
P93 A simulated bronchoscopy course for new specialist trainees
P94 Do healthcare professionals have sufficient knowledge of inhaler techniques in order to educate their patients effectively in their use?
P95 Oxygen delivery in an acute hospital setting
P96 Haplotype variability in Pseudomonas aeruginosa (Psa) strains in the adult CF population
P97 Do intravenous antibiotics influence arterial stiffness in adults with cystic fibrosis?
P98 Accuracy of routine antibiotic susceptibility testing of sputum samples in adult cystic fibrosis (CF) patients colonised with Pseudomonas aeruginosa (Psa)
P99 Social deprivation and clinical outcomes in adult CF patients
P100 An investigation of mutator Pseudomonas aeruginosa in chronically infected cystic fibrosis (CF) patients treated for pulmonary exacerbation
P101 Surface parasternal intercostal electromyogram (sEMGpara) as a monitoring tool in cystic fibrosis
P102 Quantitative biological imaging of plasmid DNA in live human airway epithelial cells following non-viral gene transfer
P103 Oral contraceptive use does not affect CF disease severity
P104 T Helper 1 and T Helper 22 cell responses against Pseudomonas aeruginosa infections
P105 Burkholderia latens—a new infection in CF patients
P106 Inflammatory markers
P109 Exercise capacity and physical activity in patients with CF
P107 Pulmonary imaging techniques to identify suitable patients and act as outcome measures in the UK CF Gene Therapy Consortium clinical programme
P108 Phenotypic changes in Pseudomonas aeruginosa (Psa) populations during exacerbations in adult Cystic Fibrosis patients infected with non-epidemic strains
P110 Quantitative PCR-based detection and quantification of atypical bacteria at baseline and exacerbation of COPD
P111 FTIR Spectroscopic profiling of COPD sputum
P112 Association of sputum Pseudomonas aeruginosa (PsA) isolation and length of hospital stay in patients with chronic obstructive pulmonary disease (COPD)
P113 Procalcitonin (PCT) is a safe and reliable biomarker of bacterial infection in exacerbations of COPD—so why is it so challenging to introduce it into a large UK hospital?
P114 C-reactive protein at onset predicts symptom resolution in acute exacerbations of COPD
P115 Vitamin D binding protein in COPD exacerbations
P116 Serum PARC (CCL18) and exacerbation frequency in COPD
P117 Comparison of indices of nutritional status in prediction of in-hospital mortality and early readmission of patients with acute exacerbations of COPD
P118 Predicting survival in patients admitted to hospital with an acute exacerbation of Chronic Obstructive Pulmonary Disease (COPD)
P119 COPD assessment test scores
P120 Observational study of acute admissions with non-infective asthma and COPD to Perth Royal Infirmary following the eruption of Icelandic volcano Eyjafjallajokull and subsequent ash cloud formation
P121 Feasibility of performing valid spirometry in rural India
P122 The use of impulse oscillometry (IOS) to study fractal scaling and sample entropy in airway resistance time series in severe asthma
P123 Impulse oscillometry (IOS) indices in severe asthma and healthy controls after deep breath manoeuvres and bronchodilator administration
P124 Neuroventilatory uncoupling during cycle and treadmill exercise in COPD
P125 Non-invasive assessment of ventilation distribution in infants using electrical impedance tomography (EIT)
P126 The influence of breathing pattern on specific airways resistance
P127 Does it matter how they breathe?—Perceptions in COPD patients when adopting different routes of breathing
P128 The challenges of hypertonic saline in non-CF bronchiectasis
P129 Lung clearance index (LCI) is a sensitive marker of early airway changes in smokers with normal spirometry
P130 Limits of agreement for peak expiratory flow measured by mini-Wright's meter and a pneumotachograph
P131 Fitness to fly assessment in patients with neuromuscular disease
P132 Carbon dioxide sensitivity in patients with hyperventilation syndrome
P133 Prediction equations for pulmonary function values in healthy Iranian children (aged 4–10 years)
P134 Lung function in post-transplant Hodgkin's lymphoma patients
P135 Lung function in post-transplant multiple myeloma patients
P136 Comparison of the ROBD and the Ventimask method of pre-flight evaluation
P137 Efficacy and safety of once-daily aclidinium bromide 200 μg in combination with formoterol in patients with COPD
P138 Efficacy of inhaled pan-selectin antagonist Bimosiamose on ozone-induced airway inflammation in healthy subjects
P139 Atelectasis following bronchoscopic lung volume reduction (BLVR) is associated with improved survival in COPD
P140 Thoracoscopic bullectomy for dyspnoea in emphysema
P141 Lung Volume reduction surgery—the first 200 operations in a UK centre
P142 Inflammatory cells in the quadriceps of COPD patients and response to resistance training
P143 NF-kappa B (NF-κB) and activator protein-1 (AP-1) DNA binding in the quadriceps of COPD patients
P144 Muscle fibre atrophy and aerobic to anaerobic fibre type shift in the quadriceps in COPD
P145 Evaluation of a quadriceps muscle endurance leg lift test in patients with chronic obstructive pulmonary disease
P146 Cognitive loss in stable non-hypoxaemic patients with moderate chronic obstructive pulmonary disease (COPD)
P147 Deprivation is associated with increased healthcare utilisation in patients with chronic obstructive pulmonary disease
P148 Correlating changes in lung function with patient reported outcomes in COPD
P149 Validation of the COPD assessment test (CAT) within α-1 antitrypsin deficiency (A1ATD)
P150 How well do patients with chronic respiratory failure secondary to COPD and their carers adapt to long-term oxygen therapy at home?
P151 Reduced mortality with β blockers when added to stepwise therapy for COPD
P152 Effect of obesity in patients admitted to Non invasive ventilation (NIV) Unit with acute hypercapnic respiratory failure (AHRF)
P153 The effect of body mass index on outcomes of acute non-invasive ventilation (NIV) in a district general hospital
P154 The patients’ experience of NIV. A phenomenological study
P155 Non-invasive ventilation (NIV) in acute hypercapnic respiratory failure in restrictive lung diseases (RLD)
P156 Does analysis of patient-ventilator interaction offer benefits in addition to overnight pulse oximetry in patients with motor neurone disease being followed on non-invasive ventilation?
P157 Staff education improves non-invasive ventilation outcomes in COPD patients presenting with acute hypercapnoeic respiratory failure.
P160 Treating TB patients with no entitlement to social support—welcome to the social jungle
P158 The strength of association between the risk of endotracheal intubation and initial arterial blood (ABG) pH in patients presenting with acute hypercapnic respiratory failure (AHRF) treated with non-invasive ventilation (NIV)
P161 Global prevalence of chronic pulmonary aspergillosis (CPA) following pulmonary tuberculosis (PTB)
P162 How many and how much? Assessing resource utilisation in Multi-drug Resistant Tuberculosis (MDR TB) management using routinely collected hospital data
P163 Incidence and clinical relevance of non-tuberculous mycobacteria isolates based on 10 years experience at York Hospital, North Yorkshire (UK)
P164 Enabling next day processing of blood samples with T-SPOT.TB
P165 TB-ST rapid test for tuberculosis diagnosis in a resource poor setting
P166 Quantiferon testing in close contacts of smear positive pulmonary TB identifies people at low risk of secondary progression
P167 Characterisation of tuberculous mediastinal lymphadenopathy on CT and correlation with biomarkers and chest radiograph findings
P168 Rifabutin is a useful alternative to rifampicin in the treatment of active TB/HIV co-infection
P169 Subclinical ocular manifestations of pulmonary and extrapulmonary tuberculosis in a Hampshire population
P170 TB-HIV co-infection
P171 The development of a UK National MDRTB service
P172 Fluticasone/salmeterol combination confers significant benefits in smoking asthmatics
P173 Management of sputum eosinophil-negative patients in a severe asthma clinic
P174 Identifying non-adherence with asthma medication and the relationship to clinical outcomes amongst adults with difficult-to-control asthma
P175 Cross-sectional and longitudinal relationships of self-management behaviours and other psychological factors with outcomes in patients with severe asthma
P176 Evaluating the role of triamcinolone in a difficult asthma service
P177 Fluticasone propionate/formoterol fumarate combination therapy is as effective as fluticasone propionate/salmeterol xinafoate in the treatment of asthma
P178 Validation of a novel synthetic absorptive matrix (SAM) for sampling nasal mucosal lining fluid
P179 Lung-based assessment in Anderson Fabry Disease (AFD) demonstrates differential α galactosidase a enzyme (GLA) activity at blood and tissue sites
P180 Sputum eosinophil positivity to tailor steroid management of severe asthmatics
P181 Better asthma control with montelukast than salmeterol in Arg-16 homozygous children with asthma
P182 Adenosine potentiates human mast cell fibrinolytic activity
P183 Global burden of allergic bronchopulmonary aspergillosis (ABPA) complicating asthma
P184 Can we predict asthma exacerbations in working-age adults?
P185 Public attitudes to smoking in cars
P186 Public attitudes to the UK smoking ban
P187 Parents support ban of smoking in cars where minors are present
P188 An evaluation of a novel semi-quantitative saliva test for cotinine and other nicotinic metabolites
P189 Smoking status predicts benefit from breathing retraining for hyperventilation
P190 Attitudes of health care professionals towards smoking cessation
P191 Development of a new patient reported experience measure for the improving lung cancer outcomes project
P192 Fibreoptic bronchoscopic insertion of the Gianturco stent for tracheobronchial obstruction in patients with cancer at a lung cancer tertiary referral centre
P193 The value of a regional mesothelioma multidisciplinary team meeting—an audit
P194 The rise of EBUS
P195 Temporal trends and distribution of recurrent disease following lung cancer surgery and relationship to pre-operative PET scan
P196 Cryo-recanalisation via day-case flexible bronchoscopy for central airway obstruction
P197 The effect of CPAP therapy on insulin sensitivity and CV risk factors in patients with OSA
P198 Effects of oxygen therapy on central sleep-disordered breathing in infants with Prader–Willi syndrome
P199 Diabetic macular oedema (DME) and obstructive sleep apnoea (OSA)—visual improvement post CPAP therapy. Proof of principle study
P200 Snoring and carotid atheroma
P201 Health literacy and sleep apnoea
P202 Clinics for obstructive sleep apnoea hypopnoea (OSAH)—time for a change?
P203 Management of obesity in respiratory clinics—are we doing enough?
P204 Travel with CPAP machines
P205 Obstructive sleep apnoea screening—cost and clinically effective in a TIA clinic?
P206 Compliance with CPAP
P207 Obstructive sleep apnoea in patients undergoing bariatric surgery—a London teaching hospital experience
P209 What might patients mean by “Sleepiness”?
P210 The national lung cancer audit—year 5 completeness and outcomes
P208 A prospective observational study to evaluate the effect of social and personality factors on CPAP compliance in OSA
P211 Assessment of operability in early stage lung cancer
P212 Screening for lung cancer
P213 Long term results of concurrent chemotherapy and hypofractionated radiotherapy for inoperable NSCLC
P214 Pathological staging of malignant pleural mesothelioma. How important is nodal disease in selection for radical surgery?
P215 The influence of age on management of lung cancer patients in England
P216 Lung cancer in young patients
P217 What's happening to lung cancer in females?
P218 Is there any value in obtaining a tissue diagnosis in suspected lung cancer patients with a performance status 3–4?
P219 Is there a role for conventional transbronchial needle aspiration in the endobronchial ultrasound era?
P220 High prevalence of malignancy in HIV infected patients with enlarged mediastinal lymphadenopathy
P221 Distal airway bacterial colonisation in patients with lung cancer
P222 A retrospective study of disease recurrence post thoracotomy for non-small cell lung cancer
P223 One blood gas is not enough to assess a patient for LTOT—how to kiss goodbye to circa £10 million in England
P224 Screening of coronary care inpatients with spirometry to detect early obstructive airways defects
P225 First national survey of the respiratory physiotherapy workforce
P226 Prevalence and treatment of pain in hospital in-patients with respiratory disease
P227 Disparities in care of adult CF patients in the UK
P228 Patient experience of a nurse led therapeutic pleural aspiration service
P229 Choose and book
P230 Inappropriate referrals to the rapid access lung clinic (RALC)
P231 Audit of pre-hospital oxygen therapy by North West Ambulance Service (NWAS) 1 year after publication of new JRCALC guidance for oxygen use
P232 The early detection of chronic obstructive pulmonary disease
P233 COPD and Me
P234 BLF and BTS “Ready for home” survey of the experiences of patients admitted to hospital with COPD. Pt2
P235 BLF and BTS “Ready for home” survey of patients admitted to hospital with COPD
P236 Allergy services at a tertiary referral centre
P237 The utility of the Nottingham Health Profile in exacerbations of non-cystic fibrosis bronchiectasis
P238 Characteristics, treatment patterns and outcomes of patients with non-CF bronchiectasis
P239 Audit of once daily nebulised hypertonic 6% saline (HTS) in adult non-CF bronchiectasis
P240 Longitudinal study of sputum microbiology in adult non-CF bronchiectasis
P241 Functional impairment in patients with bronchiectasis
P242 The treatment of pseudomonas aeruginosa (PA) in non-CF bronchiectasis
P243 Duration and choice of antibiotics in hospital admitted community acquired pneumonia patients over a period of 5 years in NHS South East of Scotland
P244 Adherence with department of health guidelines for the management of pandemic H1N1 influenza in secondary care
P245 Assessment of acute illness severity and radiological extent identify patients at heightened risk of developing major pneumonic progression in influenza A H1N1/2009 infection
P246 Suspicion-prompted testing reveals missed opportunities for diagnosing new HIV cases among patients with community-acquired pneumonia
P247 High levels of iron in the soil are associated with an increased incidence of bovine tuberculosis in cattle
P248 Measuring physical recovery in the critical care population
P249 Physicians' opinion
P250 Incidence, clinical profile and outcomes of ventilator-associated pneumonia in a tertiary hospital
P251 Flow cytometric detection of intracellular activation markers of pulmonary cells during acute lung injury
P252 A physiological characterisation of injury, inflammation and resolution in murine aspiration pneumonitis
P253 Pulmonary infiltrates in HIV negative immunocompromised patients
P254 Investigating HMGB1 as a potential inflammatory mediator in brain death induced lung damage
P255 Defining a circadian pattern of presentation of pulmonary embolism on CT/VQ imaging
P256 Investigating suspected pulmonary embolism as outpatient
P257 A comparison of scoring systems in the management of a range of pulmonary embolism patients in a university hospital
P259 Incidental findings on CT pulmonary angiography
P258 Is Chronic Thromboembolic Pulmonary Hypertension (CTEPH) under diagnosed in the UK?
P260 Managing the indeterminate CT pulmonary angiogram
P261 Questionnaire to assess acceptability of venous thromboembolism risk assessment tool by admitting doctors and nurses in the medical assessment unit of a district general hospital