The Open-Artery Hypothesis
Acute Coronary Syndromes
Pathobiology of Myocardial Necrosis
Pathobiology and Clinical Impact of Reperfusion Injury
Adjunctive Pharmacologic Treatment
Assessment of Regional Viability in the Infarct Zone Following Myocardial Infarction
Invasive Strategies to Achieve Infarct-Related Artery Patency
The Open-Artery Hypothesis
Coronary Artery Patency and Survival in Clinical Trials
The Open Artery
Early, Complete Infarct Vessel Patency
Key References in the Open-Artery Hypothesis
The Essence Trial
Prospective Comparison of Patient Characteristics and Outcome of Non-prior Aspirin Users versus Aspirin Users with Unstable Angina or Non-Q-Wave Myocardial Infarction Treated with Combination Antithrombotic Therapy
Rescue PTCA Following Failed Thrombolysis and Primary PTCA
Low-Dose Vitamin K Therapy in Excessively Anticoagulated Patients
Adjunctive Therapy with an Antithrombotic Drug Can Prevent Reocclusion and Induce Residual Thrombus Reduction After Percutaneous Transcatheter Angioplasty of the Thrombotic Lesions