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Both skipping breakfast and away-from-home (AFH) food consumption can influence diet quality. This study compared diet quality when breakfasts were eaten at home, eaten AFH, or skipped among adults (aged 32-70 years; 59% female, 62% African American) in the Healthy Aging in Neighborhoods of Diversity across the Life Span (HANDLS) study who completed two 24-hour recalls (n = 2140). Individuals who ate breakfast at home had the highest diet quality (Healthy Eating Index-2010 score). Persons who ate breakfast AFH or skipped breakfast had diet quality scores that were 3.98 and 4.62 points lower. Dietitians could promote more at-home meals as an effective strategy to improve the diet quality for Americans' breakfast.