Major histocompatibility complex typing of dogs from Russia shows further dog leukocyte antigen diversity

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Blood samples from 85 Russian dogs and wolves were collected as dried blood spots on paper and transported to the UK by mail. We obtained partial or complete three-locus canine major histocompatibility complex [dog leukocyte antigen (DLA)] class II haplotypes on 81 of these samples. Six new alleles were identified: three DLA-DRB1 and three DLA-DQB1. These alleles occurred in haplotypic combinations not previously seen in other European dogs. One haplotype appeared to lack a DQB1 allele. Two of the new haplotypes segregated through a family of dogs that was investigated.

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