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Changes in medical education have prevented students from conducting full cadaveric dissections in gross anatomy. The efficacy of alternative educational methods is being explored to augment traditional dissection.Team-based learning was integrated into the 2014 gross anatomy laboratory for physician assistants (PA) and nurse anesthetists. Deidentified data from the 2013 and 2014 courses were used to assess with t-tests the effect of this addition on student academic performance.Students in the 2014 course who experienced team-based learning performed significantly better on 75% of written and laboratory practical examinations (P < .05). Those mean examination increases correlated with a positive shift in final grades. A greater benefit was noted for PA students than for nurse anesthetist students.Team-based learning is an effective supplement to cadaveric dissection. Student short-term knowledge outcomes improve with the combination of dissection and team-based learning in the gross anatomy laboratory.