STP Achievement Award Winner
The Role of Haptic Macrophages in Regulation of Idiosyncratic Drug Reactions
Metabolic Syndrome Pathophysiology and Clinical Presentation
Distinct Functions of Vascular Endothelial and Smooth Muscle PPARγ in Regulation of Blood Pressure and Vascular Tone
A Comparative Analysis of Acute-phase Proteins as Inflammatory Biomarkers in Preclinical Toxicology Studies
Pathophysiology of Cyclooxygenase Inhibition in Animal Models
Caloric Restriction and Aging
The Liver Toxicity Biomarker Study
The Role of Protease Inhibitors in the Pathogenesis of HIV-Associated Lipodystrophy
Characterization of Hepatic Mitochondrial Injury Induced by Fatty Acid Oxidation Inhibitors
Preclinical Support for Combination Therapy in the Treatment of Autoimmunity with Atacicept
Cumulative Effects of In Utero Administration of Mixtures of “Antiandrogens” on Male Rat Reproductive Development
In Vivo/Ex Vivo and In Situ Assays Used in Cancer Research
The Novel HSP90 Inhibitor STA-9090 Exhibits Activity against KIT Dependent and Independent Malignant Mast Cell Tumors*
Establishment of High and Nonmetastasis Cell Lines Derived from Renal Cell Carcinoma of the Bhd Gene Mutant (Nihon) Rat
Canine Cardiac Rhabdomyoma
Spontaneous Hibernomas in Sprague-Dawley Rats
Analysis of Gene Expression Involved in the Enhancing Effects of Chromated Copper Arsenate on the Ultraviolet B-Induced Skin Carcinogenesis
Effects of an Antifungal Agent, Itraconazole, on Proliferative Changes of Forestomach Mucosa in Alloxan-Induced Diabetic Rats*
Morphology and Cell Lineage of Chemically Induced Atypical Thymic Hyperplasia and Lymphoma in p16INK4a/p19ARF and p53-Deficient Mice*
Chemo-Angiogenic Profile of Bovine Urinary Bladder Tumors Distinguishes Urothelial Carcinomas from Hemangiosarcomas*
Expression of the Mucin Muc4 by Tumor Cells Inhibits Apoptosis Induced by Multiple Cellular Assaults*
Urethral Transitional Carcinoma and Hyperplasia in Male B6c3f1 Mice Treated with Tetrachloroazobenzene (TCAB)*
PPARγ and Dual PPAR γ/α Agonist-Mediated Mesenchymal Tumors in Rodents: A Hypothetical Mode of Action
Mitigating Effect of Prepubertal Administration of Antithyroidal Substances on Subsequent Carcinogenic Susceptibility in Thyroid of Rats
Spontaneous Occurrence of a Malignant Seminoma in a CD1 Mouse from a Carcinogenicity Study
A Carcinogenicity Study with Unusually High Incidence of Spontaneous Hibernomas in Wistar-Han Rats
Evaluation of Histological Grade, Tumor Volume, and Markers of Inflammation and Angiogenesis to Predict Biological Activity of Canine Meningiomas
Identification and Characterization of Hoechst 33342 Side Populations in Human Malignant Mesothelioma Cell Lines
The Effect of Nitrogen Mustard on Lung and the Contribution of Proanthocyanidin to Decrease This Effect*
The Effect of Proanthocyanidin on Reexpansion Pulmonary Edema in Rats
Intimal Hyperplasia in Rats after Subcutaneous Injection of a Somatostatin Analog
Nebulization of Fungal Spores, Lipopolysaccharide, and Particles Induces Recurrent Airway Obstruction in Horses*
Safety Assessment for Compounds with Potential Cardiovascular Toxicity
Transcriptomic Signature of Endothelial Cell Damage Caused by LPS in Rat Myocardium
NMDA Inhibits Kainate-Induced Arteritis in Hearts of Mice
Rosiglitazone-Induced Myocardial Hypertrophy: A Physiologic Process? The Transcriptomic Perspective
Investigation of Cardiac Subendocardial Proliferation in the Rat and the Relevancy for Human Risk Assessment
NT-Pro Brain Natriuretic Peptide as a Biomarker for Detecting Drug-Induced Cardiac Hypertrophy in Beagle Dog
Relationship of Cardiac Troponin I Release with Histological Findings after Isoproterenol-Induced Cardiac Injury in CD1 Mice
Macroscopic Morphometry of the Heart in Beagle Dogs Used in General Toxicity Studies
The Assessment of Cardiac Changes Using the Ultra-Sensitive Troponin I Assay in Beagle Dogs
Elastosis Is a Lung Vascular Response to Chronic Exposure to Urban Air Pollution in Healthy Mice
Coronary Fibrosis: A Response to Continuous Exposure to Ambient Urban Air from Birth to Adulthood
Dose Response and Temporal Analysis of Pulmonary Lesions in Rhesus Macaques following Total Body Ionizing Radiation Exposure
Histologic Evaluation of Nasal Passages in Minipigs: Production of Optimal Sections and Characterization of Epithelia
Idiosyncratic Hepatotoxicity: A Rat Model of Converting Oxidative Stress/Reactive Metabolites to Hepatotoxicants
Gypsophila L. Induces Hepatocellular Damage in Balb/C Mice
Characterization of Rat Liver Treated with Butylated Hydroxyanisole and Phenobarbital by Toxicogenomic and Toxicoproteomic Analysis
T-2 Toxin-Induced Hepatotoxicity in Mice: Histopathology and Gene Expression Profile
Adaptive Physiologic Hypertrophic Response in the Liver, Thyroid Gland, and Pituitary Gland to Hepatocellular Microsomal Enzyme Induction in Rats
Macrophage Appearance and Monocyte Chemoattractant Protein-1 in Thioacetoamide-Induced Rat Hepatic Injury
Hepatic Mallory-Denk Body Formation in a Streptozotocin-Treated Vervet Monkey ( Chlorocebus aethiops )*
Acquired Resistance to Acetaminophen Hepatotoxicity Is Associated with Induction of Multidrug Resistance Protein 4 (Mrp4) in Proliferating Hepatocytes
Quantitative Assessment of Adipophilin Immunohistochemistry in a Rodent Model of Steatohepatitis
Mechanistic Investigation for the Species-Specific Hyperbilirubinemia Induced by MLN8054
Inflammatory and Chloracne-Like Skin Lesions in B6C3F1 Mice Exposed to Tetrachloroazobenzene (TCAB) for Two Years*
Gypsophila L.-Containing Diet Reduces Glutathione Peroxidase Activity in Balb/C Mice*
Immunotoxicity and Induction of Apoptosis by Subchronic Exposure of Organophosphate Compounds
Spontaneous Changes in the Retinal Pigment Epithelium of Dutch Rabbits
Tapetal Changes in Beagle Dogs following Oral Administration of a Discontinued Antidiabetic Drug
Effects of Opium Addiction on Some Serum Factors of Alloxan-Induced Diabetic Rats
Assessment of Skin Toxicity in Monkeys Treated with PF-00734200, a Selective DPP-4 Inhibitor
Mechanism of Neuronal Cell Apoptosis in the 6-Mp-Treated Fetal Rat Brain
Neuropathology in the Nose and Brain of Mice Repeatedly Exposed to the Macrocyclic Trichothecene Mycotoxin, Roridin A
Novel Implication of the Inflammatory System in Ciguatera Fish Poisoning*
Microangiopathy Associated with Drug-Induced Retinal Degeneration in Rats and Mice
Relation between Eosinophilic Substance and Vomeronasal Organ in Mouse Nasal Septum
5-Fluorouracil Induces Apoptosis and Depression of Proliferation Activity of Neuroepithelial Cells in the Rat Fetal Brain
Comparison between Light Microscopy (LM), Electron Microscopy (TEM) and Flow Cytometry in the Analysis of Peripheral Leucocytes in a Rat Model of Amiodarone-Induced Phospholipidosis
Kainic Acid-Induced F-344 Rat Model of Mesial Temporal Lobe Epilepsy: Gene Expression and Canonical Pathways*
Choristoma (Epidermoid) in the Fourth Ventricle of a Beagle Dog
Evaluation of Genotoxicity Induced by Atrazine in Rat Tissues: Attenuation by Vitamin E
Characterization of Phospholipidosis in Skeletal Muscle Induced in the Rat by Chronic Exposure to Chloroquine
Treatment of Osteomyelitis in Rats by Injection of Degradable Polymer-Releasing Gentamicin
Metabolomic Profiles of Liver and Plasma following Whole-Liver Irradiation in Mice
GLP Compliance with Virtual Slides
Development of a Xenoestrogen-Responsive Transient Zebrafish Using the Brain Aromatase-Based Reporter Gene
Gene Expression Profile in Iprobenfos-Exposed Medaka Fish by Microarray Analysis
Estimation of Probabilistic Risk Assessment of Korean Female Overall Dermal Exposure in Cosmetic Usage*
Screening of Differentially Expressed Genes of Fathead Minnow Exposed to Hexahydro-1,3,5-Trinitro-1,3,5-Triazine Using Microarray
Statistical Model for In Vitro Toxicity Assessment of Root Canal Materials in Animals
Morbidity, Mortality, Tumor, and Pathology Trends in Control Sprague-Dawley [Crl: CD (SD)] Rats from 1977 to 2006 under Ad Libitum Overfeeding and Controlled Feeding to Manage Comorbidities and Control Spontaneous Tumor Profiles in the CD Rat Model
Nature via Nurture: the CD Rat as a Polygenetic Model of Dietary-Induced Obesity (DIO) and the Modulation of Phenotype with Dietary Control in Safety Assessment
Computer-Assisted Quantitative Analysis of Digital Whole Tissue Section Images of Rat Liver
Pathophysiological Continuum Framework for Selected Toxicological Endpoints Used in Risk Assessments
Whole-Slide Image Analysis with Smart Tissue Finding on Common Toxicological Problems
Metabolic Labeling of Newly Synthesized Collagen with Deuterium Is a Useful Tool for Detection and Quantification of Fibrosis in a Rat Model of Chronic Allograft Rejection
Aspects of Background Pathology in the Göttingen Minipig
Performance of a Novel Automated Microvessel Analysis Algorithm across Whole-Slide Digital Images
Safety Assessment of Novel Bioflavonoids Using the Threshold of Toxicologic Concern Approach
Incidences and Range of Spontaneous Lesions in Control Purpose-Bred Cynomolgus Monkeys ( Macaca fascicularis ) Used in Toxicity Studies
Multiparameter Automated Analysis of Chromatically Stained Tissue Sections by Laser-Scanning Cytometry
Regression of Advanced Liver Fibrosis by a Simple Plasmid-Mediated Metallothionein Gene Therapy in Mice*
The Fungal Metabolite, Pyrrocidine A, Induces Apoptosis in HepG2 Hepatocytes and PK15 Renal Cells
Toxicological Properties of a Commonly Used Live-Cell Dye Hoechst 33342
Drug-Induced Hemolytic Effects Evaluated in a Rat and Human Hemolysis Model
Diagnostic Criteria for Peroxisome Proliferator-Activated Receptor (PPAR) Agonist-Induced Urothelial Lesions in Cynomolgus Monkeys
Guidance for Histopathologic Detection of Endocrine Disruption of the Male Reproductive System in the Updated OECD 28-Day Oral Toxicity Study in Rodents (TG 407)
Guidance for Histopathologic Detection of Endocrine Disruption of the Female Reproductive System in the Updated OECD 28-Day Oral Toxicity Study in Rodents (TG 407)
Guidance for Histopathologic Detection of Endocrine Disruption of the Mammary Gland and Pituitary in the Updated OECD 28-Day Oral Toxicity Study in Rodents (TG 407)
The Comparative Signaling Role of p38 MAP Kinases in the Female Reproductive System
Morphologic, Clinical Pathologic, and Gene Expression Changes Indicative of Xenobiotic-Associated Effects on Renal Ion Transporters in the Rat
The Water Extract of Paecilomyces tenuipes Induced Morphological Changes of Kidney in Sprague-Dawley Rats
Renal Alpha 2u-Globulin Expression in Male Sprague-Dawley Rats
Morphological and Functional Changes of Exocrine Pancreas Injury in Cynomologus Monkeys Treated with a Cyclin-Dependent Kinase Inhibitor
Evaluation of Molecular Markers of Renal Toxicity Caused by Segment-Specific Nephrotoxicants for the Proximal Tubule
Effect of Sewage Sludge Biosolid in Mice Spermatogenesis
KIM-1: Mechanistic Marker of Acute Nephrotoxicity in Male Rats following Two-Week d-Limonene Administration
Apoptosis in Different Stages of Seminiferous Epithelia of Mice Chronically Exposed During Pre- and Postnatal Periods to Ambient Levels of Traffic-Related Particles
Using In Vitro Thyroid Cultures, Both Rat and Human, to Evaluate Drug-Induced Thyroid Effects and Species Differences