SNPs and Chips: Genomic Data in Safety Evaluation and Risk Assessment
Workshop Overview: Use of Genomic Data in Risk Assessment
The Road to Elucidating the Mechanism of Manganese-Bilirubin–Induced Cholestasis
Type 1 Diabetic Mice Are Protected from Acetaminophen Hepatotoxicity
Predicting Fetal Perchlorate Dose and Inhibition of Iodide Kinetics during Gestation: A Physiologically-Based Pharmacokinetic Analysis of Perchlorate and Iodide Kinetics in the Rat
PBPK Predictions of Perchlorate Distribution and Its Effect on Thyroid Uptake of Radioiodide in the Male Rat
Characterization of the Pharmacokinetic and Pharmacodynamic Interaction between Gamma-Hydroxybutyrate and Ethanol in the Rat
Neonatal Ontogeny of Murine Arylamine N-Acetyltransferases: Implications for Arylamine Genotoxicity
Hepatocellular Tumor Induction in Heterozygous p53-Deficient CBA Mice by a 26-Week Dietary Administration of Kojic Acid
Metallothionein Is a Potential Negative Regulator of Apoptosis
Stochastic Simulation of Hepatic Preneoplastic Foci Development for Four Chlorobenzene Congeners in a Medium-Term Bioassay
A New Approach to Studying Ochratoxin A (OTA)-Induced Nephrotoxicity: Expression Profiling in Vivo and in Vitro Employing cDNA Microarrays
Effects of Intermittent Exposure to Aflatoxin B1 on DNA and RNA Adduct Formation in Rat Liver: Dose-Response and Temporal Patterns
The Effect of Cigarette Smoke Exposure and Ascorbic Acid Intake on Gene Expression of Antioxidant Enzymes and Other Related Enzymes in the Livers and Lungs of Shionogi Rats with Osteogenic Disorders
Effects of Minimally Toxic Levels of Carbonyl Cyanide P-(Trifluoromethoxy) Phenylhydrazone (FCCP), Elucidated through Differential Gene Expression with Biochemical and Morphological Correlations
Immunotoxicity of Aflatoxin B1 in Rats: Effects on Lymphocytes and the Inflammatory Response in a Chronic Intermittent Dosing Study
Synergistic Role of 3-Hydroxy-3-Methylglutaryl Coenzyme A Reductase and Cholesterol 7α-Hydroxylase in the Pathogenesis of Manganese-Bilirubin–Induced Cholestasis in Rats
Gene Expression in Two Hepatic Cell Lines, Cultured Primary Hepatocytes, and Liver Slices Compared to the in Vivo Liver Gene Expression in Rats: Possible Implications for Toxicogenomics Use of in Vitro Systems
Disassociation of Carbon Disulfide-Induced Depression of Flash-Evoked Potential Peak N166 Amplitude and Norepinephrine Levels
In Vivo and in Vitro Effects of Melatonin or Ganglioside GT1B on L-Cysteine–Induced Brain Mitochondrial DNA Damage in Mice
Expression and Activity of Cytochromes P450 2E1, 2A, and 2B in the Mouse Ovary: The Effect of 4-Vinylcyclohexene and Its Diepoxide Metabolite
Quantitative Changes in Gene Expression in Fetal Rat Testes following Exposure to Di(n-butyl) Phthalate
The Embryolethality of Lipopolysaccharide in CD-1 and Metallothionein I–II Null Mice: Lack of a Role for Induced Zinc Deficiency or Metallothionein Induction
The Effect of Lung Structure on Mucociliary Clearance and Particle Retention in Human and Rat Lungs