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Site-Specific, Dose-Dependent Transitional Analysis of Toxicologic Mechanisms: The Interplay of Local Metabolic and Physicochemical Saturation
Trichloroethylene: Mechanisms of Renal Toxicity and Renal Cancer and Relevance to Risk Assessment
Increasing Exposure Levels Cause an Abrupt Change in the Absorption and Metabolism of Acutely Inhaled Benzo(a)pyrene in the Isolated, Ventilated, and Perfused Lung of the Rat
Absorption, Distribution, Metabolism, and Elimination of 8-2 Fluorotelomer Alcohol in the Rat
Ginsenoside Metabolites, Rather Than Naturally Occurring Ginsenosides, Lead to Inhibition of Human Cytochrome P450 Enzymes
Adenovirus-Mediated Expression of CYP2E1 Produces Liver Toxicity in Mice
Chronic Oral Exposure to Inorganic Arsenate Interferes with Methylation Status of p16INK4a and RASSF1A and Induces Lung Cancer in A/J Mice
4-Nitroquinoline 1-Oxide Forms 8-Hydroxydeoxyguanosine in Human Fibroblasts through Reactive Oxygen Species
Phenobarbital Induces Progressive Patterns of GC-Rich and Gene-Specific Altered DNA Methylation in the Liver of Tumor-Prone B6C3F1 Mice
Altered Methylation in Gene-Specific and GC-Rich Regions of DNA Is Progressive and Nonrandom during Promotion of Skin Tumorigenesis
Differential Expression Patterns of Wnt and β-Catenin/TCF Target Genes in the Uterus of Immature Female Rats Exposed to 17α-Ethynyl Estradiol
Fasting Augments PCB Impact on Liver Metabolism in Anadromous Arctic Char
Formation of Genotoxic Nitro-PAH Compounds in Fish Exposed to Ambient Nitrite and PAH
The Mycoestrogen Zearalenone Induces CYP3A through Activation of the Pregnane X Receptor
Effects of Neonatal Exposure to 4-Tert-Octylphenol, Diethylstilbestrol, and Flutamide on Steroidogenesis in Infantile Rat Testis
Metallothionein-1 and -2 Expression in Cadmium- or Arsenic-Derived Human Malignant Urothelial Cells and Tumor Heterotransplants and as a Prognostic Indicator in Human Bladder Cancer
Mitochondrial and Nuclear DNA Damage Induced by Curcumin in Human Hepatoma G2 Cells
Trichostatin A Enhances Gap Junctional Intercellular Communication in Primary Cultures of Adult Rat Hepatocytes
Inducible Nitric Oxide Synthase and Apoptosis in Murine Proximal Tubule Epithelial Cells
Identification of New Human Pregnane X Receptor Ligands among Pesticides Using a Stable Reporter Cell System
Surface Reactivity, Cytotoxic, and Morphological Transforming Effects of Diatomaceous Earth Products in Syrian Hamster Embryo Cells
Manganese-Induced Neurotoxicity: The Role of Astroglial-Derived Nitric Oxide in Striatal Interneuron Degeneration
Imaging the Peripheral Benzodiazepine Receptor Response in Central Nervous System Demyelination and Remyelination
Effect of Ketamine on Dendritic Arbor Development and Survival of Immature GABAergic Neurons In Vitro
Radiation Exposure Impairs Luteinizing Hormone Signal Transduction and Steroidogenesis in Cultured Human Leydig Cells
Macaque Trophoblast Migration toward RANTES Is Inhibited by Cigarette Smoke–Conditioned Medium
The Effect of Perinatal TCDD Exposure on Caries Susceptibility in Rats
Application of Physiologically Based Pharmacokinetic Modeling in Setting Acute Exposure Guideline Levels for Methylene Chloride
Chronic Administration of Belimumab, a BLyS Antagonist, Decreases Tissue and Peripheral Blood B-Lymphocyte Populations in Cynomolgus Monkeys: Pharmacokinetic, Pharmacodynamic, and Toxicologic Effects
Chemical Boundaries for Detection of Eye Irritation in Humans from Homologous Vapors
Biodistribution of DNA Plasmid Vaccines against HIV-1, Ebola, Severe Acute Respiratory Syndrome, or West Nile Virus Is Similar, without Integration, despite Differing Plasmid Backbones or Gene Inserts
Toxicological Safety Evaluation of DNA Plasmid Vaccines against HIV-1, Ebola, Severe Acute Respiratory Syndrome, or West Nile Virus Is Similar Despite Differing Plasmid Backbones or Gene-Inserts
Dietary Modulation of p-Nonylphenol–Induced Polycystic Kidneys in Male Sprague-Dawley Rats
Mitochondrial Thioredoxin-2 Has a Key Role in Determining Tumor Necrosis Factor-α–Induced Reactive Oxygen Species Generation, NF-κB Activation, and Apoptosis
Tienilic Acid Enhances Hyperbilirubinemia in Eisai Hyperbilirubinuria Rats through Hepatic Multidrug Resistance–Associated Protein 3 and Heme Oxygenase-1 Induction