Accelerating the Development of 21st-Century Toxicology
Identification of Urinary microRNA Profiles in Rats That May Diagnose Hepatotoxicity
Bioactivation versus Detoxication of the Urothelial Carcinogen Aristolochic Acid I by Human Cytochrome P450 1A1 and 1A2
Parallel Biotransformation of Tetrabromobisphenol A in Xenopus laevis and Mammals
Lentiviral-Mediated RNAi Knockdown Yields a Novel Mouse Model for Studying Cyp2b Function
Aberrant Expression of miR-638 Contributes to Benzo(a)pyrene-Induced Human Cell Transformation
2-Amino-3-Methylimidazo[4,5-f]Quinoline (IQ) Promotes Mouse Hepatocarcinogenesis by Activating Transforming Growth Factor-β and Wnt/β-Catenin Signaling Pathways
Aryl Hydrocarbon Receptor Modulation of Estrogen Receptor α-Mediated Gene Regulation by a Multimeric Chromatin Complex Involving the Two Receptors and the Coregulator RIP140
Analysis of Aberrant Methylation in DNA Repair Genes During Malignant Transformation of Human Bronchial Epithelial Cells Induced by Cadmium
An NF-κB–Independent and Erk1/2-Dependent Mechanism Controls CXCL8/IL-8 Responses of Airway Epithelial Cells to Cadmium
Transcriptomic Concentration-Response Evaluation of Valproic Acid, Cyproconazole, and Hexaconazole in the Neural Embryonic Stem Cell Test (ESTn)
Selective Activation of Zebrafish Estrogen Receptor Subtypes by Chemicals by Using Stable Reporter Gene Assay Developed in a Zebrafish Liver Cell Line
Aerosolized ZnO Nanoparticles Induce Toxicity in Alveolar Type II Epithelial Cells at the Air-Liquid Interface
Zinc Oxide Nanoparticles Interfere With Zinc Ion Homeostasis to Cause Cytotoxicity
Cypermethrin Induces Astrocyte Apoptosis by the Disruption of the Autocrine/Paracrine Mode of Epidermal Growth Factor Receptor Signaling
Dickkopf 1 Mediates Glucocorticoid-Induced Changes in Human Neural Progenitor Cell Proliferation and Differentiation
Subchronic Polychlorinated Biphenyl (Aroclor 1254) Exposure Produces Oxidative Damage and Neuronal Death of Ventral Midbrain Dopaminergic Systems
Mixed Inhibition of Adenosine Deaminase Activity by 1,3-Dinitrobenzene
Arsenic Exposure to Killifish During Embryogenesis Alters Muscle Development
Epigenetic Alterations in Sperm DNA Associated with Testicular Cancer Treatment
Genomic Biomarkers of Phthalate-Induced Male Reproductive Developmental Toxicity
Divergent Electrocardiographic Responses to Whole and Particle-Free Diesel Exhaust Inhalation in Spontaneously Hypertensive Rats
The Role of MAPK and Nrf2 Pathways in Ketanserin-Elicited Attenuation of Cigarette Smoke–Induced IL-8 Production in Human Bronchial Epithelial Cells
A Selective Akt Inhibitor Produces Hypotension and Bradycardia in Conscious Rats Due to Inhibition of the Autonomic Nervous System
Rat-Specific Decreases in Platelet Count Caused by a Humanized Monoclonal Antibody Against Sclerostin
Doxorubicin Increases Oxidative Metabolism in HL-1 Cardiomyocytes as Shown by 13C Metabolic Flux Analysis
Exacerbation of Acetaminophen Hepatotoxicity by the Anthelmentic Drug Fenbendazole