Identification and Characterization of Adverse Effects in 21st Century Toxicology
Antifungal Miconazole Induces Cardiotoxicity Via Inhibition of APE/Ref-1-Related Pathway in Rat Neonatal Cardiomyocytes
Metabolic Profiling of the Rat Liver After Chronic Ingestion of Alpha-Naphthylisothiocyanate Using In Vivo and Ex Vivo Magnetic Resonance Spectroscopy
Pharmacokinetics of Melamine and Cyanuric Acid and Their Combinations in F344 Rats
Rat Brain CYP2B-Enzymatic Activation of Chlorpyrifos to the Oxon Mediates Cholinergic Neurotoxicity
Identification and Pathway Mapping of Furan Target Proteins Reveal Mitochondrial Energy Production and Redox Regulation as Critical Targets of Furan Toxicity
The Anabolic Androgenic Steroid Fluoxymesterone Inhibits 11β-Hydroxysteroid Dehydrogenase 2–Dependent Glucocorticoid Inactivation
Proinflammatory Adhesion Molecules Facilitate Polychlorinated Biphenyl–Mediated Enhancement of Brain Metastasis Formation
Mechanism of Inhibition of the ATPase Domain of Human Topoisomerase IIα by 1,4-Benzoquinone, 1,2-Naphthoquinone, 1,4-Naphthoquinone, and 9,10-Phenanthroquinone
Inherent and Benzo[a]pyrene-Induced Differential Aryl Hydrocarbon Receptor Signaling Greatly Affects Life Span, Atherosclerosis, Cardiac Gene Expression, and Body and Heart Growth in Mice
Dose-Response Assessment of Naphthalene-Induced Genotoxicity and Glutathione Detoxication in Human TK6 Lymphoblasts
Differential Gene Expression Responses Distinguish Contact and Respiratory Sensitizers and Nonsensitizing Irritants in the Local Lymph Node Assay
Novel Application of Human Neurons Derived from Induced Pluripotent Stem Cells for Highly Sensitive Botulinum Neurotoxin Detection
Intracellular Pb2+ Content Monitoring Using a Protein-Based Pb2+ Indicator
Antibody-Mediated Inhibition of Fibroblast Growth Factor 19 Results in Increased Bile Acids Synthesis and Ileal Malabsorption of Bile Acids in Cynomolgus Monkeys
Effects of Silver Nanoparticles on Primary Mixed Neural Cell Cultures
Zeta Potential and Solubility to Toxic Ions as Mechanisms of Lung Inflammation Caused by Metal/Metal Oxide Nanoparticles
Cadmium Associated With Inhaled Cadmium Oxide Nanoparticles Impacts Fetal and Neonatal Development and Growth
Differential Effects of 20 Non–Dioxin-Like PCBs on Basal and Depolarization-Evoked Intracellular Calcium Levels in PC12 Cells
Repeated Exposure to Sublethal Doses of the Organophosphorus Compound VX Activates BDNF Expression in Mouse Brain
Differing Effects of Toxicants (Methylmercury, Inorganic Mercury, Lead, Amyloid β, and Rotenone) on Cultured Rat Cerebrocortical Neurons
Efficacy Assessment of Various Anticholinergic Agents Against Topical Sarin-Induced Miosis and Visual Impairment in Rats
Synthesis and In Vitro and In Vivo Inhibition Potencies of Highly Relevant Nerve Agent Surrogates
Functional Rehabilitation of Cadmium-Induced Neurotoxicity Despite Persistent Peripheral Pathophysiology in the Olfactory System
Differences in Radiation Sensitivity of Recovery of Spermatogenesis Between Rat Strains
Aryl Hydrocarbon Receptor (AhR) Regulates Silica-Induced Inflammation But Not Fibrosis
DNA Double-Strand Breaks and DNA Recombination in Benzene Metabolite–Induced Genotoxicity
Quantitative High-Throughput Screening for Chemical Toxicity in a Population-Based In V itro Model
Protein Phosphatase 2A Regulates Innate Immune and Proteolytic Responses to Cigarette Smoke Exposure in the Lung