The Hazards of Playing It Safe
Incorporating New Technologies Into Toxicity Testing and Risk Assessment
SLCO1B1 Variants and Urine Arsenic Metabolites in the Strong Heart Family Study
Temporal Changes in K-ras Mutant Fraction in Lung Tissue of Big Blue B6C3F1 Mice Exposed to Ethylene Oxide
A New Player in Environmentally Induced Oxidative Stress
Roles of the Hemostatic System and Neutrophils in Liver Injury From Co-exposure to Amiodarone and Lipopolysaccharide
The Nrf2 Activator, tBHQ, Differentially Affects Early Events Following Stimulation of Jurkat Cells
Pretreatment With TCDD Exacerbates Liver Injury From Concanavalin A
Microcystin-LR Exhibits Immunomodulatory Role in Mouse Primary Hepatocytes Through Activation of the NF-κB and MAPK Signaling Pathways
Development of an Adverse Outcome Pathway From Drug-Mediated Bile Salt Export Pump Inhibition to Cholestatic Liver Injury
Genome-Wide RNAi High-Throughput Screen Identifies Proteins Necessary for the AHR-Dependent Induction of CYP1A1 by 2,3,7,8-Tetrachlorodibenzo-p-dioxin
Relating Cytotoxicity, Zinc Ions, and Reactive Oxygen in ZnO Nanoparticle–Exposed Human Immune Cells
Accumulated Polymer Degradation Products as Effector Molecules in Cytotoxicity of Polymeric Nanoparticles
Stimulation-Evoked Dopamine Release in the Nucleus Accumbens Following Cocaine Administration in Rats Perinatally Exposed to Polychlorinated Biphenyls
Aberration in Epigenetic Gene Regulation in Hippocampal Neurogenesis by Developmental Exposure to Manganese Chloride in Mice
Impairment of Atg5-Dependent Autophagic Flux Promotes Paraquat- and MPP+-Induced Apoptosis But Not Rotenone or 6-Hydroxydopamine Toxicity
Treatment With Anticancer Agents Induces Dysregulation of Specific Wnt Signaling Pathways in Human Ovarian Luteinized Granulosa Cells In Vitro
Activation of Autophagy Rescues Amiodarone-Induced Apoptosis of Lung Epithelial Cells and Pulmonary Toxicity in Rats
Concordance of Transcriptional and Apical Benchmark Dose Levels for Conazole-Induced Liver Effects in Mice
A Multifactorial Approach to Hepatobiliary Transporter Assessment Enables Improved Therapeutic Compound Development
Quantitative Structure-Activity Relationship Models for Predicting Drug-Induced Liver Injury Based on FDA-Approved Drug Labeling Annotation and Using a Large Collection of Drugs
A Novel Mouse Model for Phenytoin-Induced Liver Injury