In vitro screening of 200 pesticides for agonistic activity via mouse peroxisome proliferator-activated receptor (PPAR)α and PPARγ and quantitative analysis of in vivo induction pathway
Effect of proteasome inhibition on toxicity and CYP3A23 induction in cultured rat hepatocytes: Comparison with arsenite
In vitro toxicity of silica nanoparticles in human lung cancer cells
Strain differences in the responsiveness between Sprague-Dawley and Fischer rats to nephropathy induced by FYX-051, a xanthine oxidoreductase inhibitor
Acrolein induces vasodilatation of rodent mesenteric bed via an EDHF-dependent mechanism
Acrolein generation stimulates hypercontraction in isolated human blood vessels
Diquat induces renal proximal tubule injury in glutathione reductase-deficient mice
Differences in gene expression profiles in the liver between carcinogenic and non-carcinogenic isomers of compounds given to rats in a 28-day repeat-dose toxicity study
Developmental toxicity of 4-ring polycyclic aromatic hydrocarbons in zebrafish is differentially dependent on AH receptor isoforms and hepatic cytochrome P4501A metabolism
Critical role of free cytosolic calcium, but not uncoupling, in mitochondrial permeability transition and cell death induced by diclofenac oxidative metabolites in immortalized human hepatocytes
The coffee diterpene kahweol inhibits tumor necrosis factor-α-induced expression of cell adhesion molecules in human endothelial cells
Co-cultivation of Streptomyces californicus and Stachybotrys chartarum stimulates the production of cytostatic compound(s) with immunotoxic properties
Dexamethasone hepatic induction in rats subsequently treated with high dose buprenorphine does not lead to respiratory depression
TCDD decreases ATP levels and increases reactive oxygen production through changes in mitochondrial F0F1-ATP synthase and ubiquinone
The expression of Hedgehog genes ( Ihh , Dhh ) and Hedgehog target genes ( Ptc1 , Gli1 , Coup-TfII ) is affected by estrogenic stimuli in the uterus of immature female rats