Antioxidant role of glutathione S-transferases: 4-Hydroxynonenal, a key molecule in stress-mediated signaling
Superoxide produced in the matrix of mitochondria enhances methylmercury toxicity in human neuroblastoma cells
Genetic variation in metallothionein and metal-regulatory transcription factor 1 in relation to urinary cadmium, copper, and zinc
H2S induces vasoconstriction of rat cerebral arteries via cAMP/adenylyl cyclase pathway
Arsenic induces structural and compositional colonic microbiome change and promotes host nitrogen and amino acid metabolism
Selenite exacerbates hepatic insulin resistance in mouse model of type 2 diabetes through oxidative stress-mediated JNK pathway
Omeprazole increases the efficacy of a soluble epoxide hydrolase inhibitor in a PGE2 induced pain model
Application of physiologically-based pharmacokinetic modeling to explore the role of kidney transporters in renal reabsorption of perfluorooctanoic acid in the rat
Development of a physiologically based pharmacokinetic model for assessment of human exposure to bisphenol A
Exposure to coplanar PCBs induces endothelial cell inflammation through epigenetic regulation of NF-κB subunit p65
The estrogen-dependent baroreflex dysfunction caused by nicotine in female rats is mediated via NOS/HO inhibition: Role of sGC/PI3K/MAPKERK
Osthole promotes neuronal differentiation and inhibits apoptosis via Wnt/β-catenin signaling in an Alzheimer's disease model
Resveratrol alleviates diabetes-induced testicular dysfunction by inhibiting oxidative stress and c-Jun N-terminal kinase signaling in rats
Effects of sexually dimorphic growth hormone secretory patterns on arachidonic acid metabolizing enzymes in rodent heart
Exposure to bisphenol A in young adult mice does not alter ovulation but does alter the fertilization ability of oocytes
Low dose evaluation of the antiandrogen flutamide following a Mode of Action approach
Application of electroretinography (ERG) in early drug development for assessing retinal toxicity in rats
Toxicological responses of environmental mixtures: Environmental metal mixtures display synergistic induction of metal-responsive and oxidative stress genes in placental cells
Diacetyl and 2,3-pentanedione exposure of human cultured airway epithelial cells: Ion transport effects and metabolism of butter flavoring agents
19-Hydroxyeicosatetraenoic acid and isoniazid protect against angiotensin II-induced cardiac hypertrophy
Doxorubicin: Comparison between 3-h continuous and bolus intravenous administration paradigms on cardio-renal axis, mitochondrial sphingolipids and pathology
Carbon black nanoparticles induce biphasic gene expression changes associated with inflammatory responses in the lungs of C57BL/6 mice following a single intratracheal instillation