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The number of the patients in need of organ transplantation continuously increases as a result of organ failure due to various diseases which can be remedied by transplant. The lack of donors results in patient fatality while waiting for transplant. Our objective is to increase the number of organ donation through bringing the importance of this issue to the attention of Health Professionals and public at large in Samsun Organ and Tissue Transplantation Regional Coordination Centre (SOTTRC-Centre) in the first instance.Table 1 shows the population distribution in 2011 (start of public awareness campaign) and 2016 in the SOTTRC-Centre region. Table 2 shows the corresponding demographic data of cadaveric donors. Two proportion statistical process is used to analyze the data in estimating the number of donors per million of population (pmp). In order to increase the number of donors in the cities comprising SOTTRC, we have organized several seminars, conferences and panels. Due to the importance of religious belief in organ donation, educational programs were conducted by the religious and spiritual leaders. Doctors, Organ Transplantation Coordinators and other health professionals were also informed about the difficulties and needs of the matter. Financed by The European Union and The Ministry of Health of Turkish Republic, these information seminars, called “Technical Assistance for Alignment in Organ Donation” were attended by some 150 health professionals including Anesthesiologists, Neurologists, Neurosurgeons and Intensivists. With the help of the project ‘Donate and Eliminate the Obstacles’, 4604 people were informed about organ transplantation. Organ Transplantation Coordinators gave seminars on organ transplantation and brain death in all public institutions in the SOTTRC region, enhanced by television and radio coverage as well as Organ Transplantation Stands and information seminars in schools and colleges.Demographic data are shown in Table 2. There are no differences between groups in terms of age and gender. As shown in Table 3, the number of cadaveric donors increased significantly from 3.47 pmp in 2011 to 8.65 pmp in 2016 with p=0.001.As a consequence; it is crucial to raise awareness about the organ transplantation in every segment of society. People and professionals on the field should be educated regularly. These efforts can lead to a significant increase in the number of organ transplantation. We believe that educational seminars, panels and meetings held on this issue have resulted in public acceptance of organ donation resulting in increased organ transplantation.