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Organ donation is the most important stage for organ transplantation. Studies reveal that brain-dead patients’ families’ attitude towards donation plays a significant role in decision-making Add Reference 1. The main reasons for denial of donation were insufficient knowledge about brain death, religious beliefs and breaching the body integrity Add Reference 2. We hypothesized that supporting family awareness about the meaning of organ donation, saving lives while losing a loved one, combined with being informed about the brain death and donation process must be maintained by the intensivist through standardized interviews and questionnaires in order to increase the donation rate. We aimed to demonstrate the importance of standardizing the interviews with the potential brain-dead donor’s relatives regarding the decision to donate. We evaluated the final decision of the families of the brain-dead donors in our institution during a three-year period.This retrospective study is conducted in Marmara University Hospital Intensive Care Units between 2014-2017. Standard interview content was generated after literature were reviewed by the authors Add Figure 1. The families of 52 intubated organ donor patients were included in the study. Data were presented after descriptive analyses.Five families out of 17 donated (29,4%) organs of their brain-dead relative’s when standardized interviews were used. In this group (Group S), GCS<5 patients’ families were informed 3 times daily. The first interviews done after brain death diagnosis lasted 16,1±6 (10-30) minutes and a second interview was done with the hesitant families lasting 10±4 (5-15) minutes. During this period, they were able to see their relatives 2-5 times daily. In the other group (Group NS), intensivists governed informing the families while interviews were not standardized. During this period families were informed once or twice daily and could see their patient once a day. The approximate interview duration was 10-15 minutes. Five families out of 35 brain dead patients’ families (14,3%) approved organ donation.Standard interviews between the relatives of the brain-dead donors and the intensivists, combined with facilitating relatives’ visit to their patients, and being informed about him/her result in an increased rate of organ donation when compared to routine protocols.1. Siminoff LA, Gordon N, Hewlett J, Arnold RM. Factors influencing families' consent for donation of solid organs for transplantation. JAMA. 2001 Jul 4;286(1):71-7.2. Birtan D, Arslantas MK, Dincer PC, Altun GT, Bilgili B, Ucar FB, Bozoklar CA, Ayanoglu HO. Effect of Interviews Done by Intensive Care Physicians on Organ Donation. Transplant Proc. 2017 Apr;49(3):396-398.