Complete Blood Count of Deceased Donors and the Results of Liver Transplantation

    loading  Checking for direct PDF access through Ovid

Abstract

Introduction

Evaluating donor characteristics is mandatory for the recipients’ safety and aiding predicting outcomes. The aim was to assess whether abnormalities in complete blood count (CBC) of DBD liver donor present risk factors.

Methods

Early and long-term results [1-year recipient (1RS+/1RS-) and graft (1GS+/1GS-) survival, 5-year recipient (5RS+/5RS-) and graft (5GS+/5GS-) survival rates] of liver transplantation were evaluated in connection with donor CBC [HGB (g/dl), HCT (%), WBC(k/mm3), PLT(k/mm3)] respectively for 2804 transplantations in the years 1998‐2013 and 1724 in the years 1998‐2009. Data originated from Poltransplant’s records.

Results

Figure.1

Conclusions

1. Abnormalities in donor CBC do not influence the early and long-term recipient survival. 2.PLT does not affect the early and long-term transplant outcomes. 3.WBC affects early and late graft survival; reaches lower values in donors providing recipients with at least 1 and 5-year graft function, possibly because of the corresponding risk of infection transmission. 4.Significant deviations of HGB and HCT in groups of grafts that survived and not survived five years, do not display clinical justification.

Related Topics

    loading  Loading Related Articles