Comparative Analysis of Postoperative Complications after Kidney Transplantation: Uncontrolled DCD vs DBD Grafts, are they the Same?

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Abstract

Methods

We carried out a retrospective review of 300 KT (150 uDCD with normothermic perfusion and 150 DBD) performed in our centre between 2007 and 2012 on recipients under 60 years old. We collected preoperative features, surgical technique, graft characteristics and postoperative complications. These complications were also stratified according to time of onset (early –during the first 90 postoperative days– versus late –after the 90th postoperative day–) and severity (based on Clavien-Dindo classification). Data were analysed using Stata v12.0 for Windows.

Results

Baseline characteristics were comparable, with a median follow-up of 53.6 months. Total postoperative complication rate was 77.7%. Comparative incidence of complications is presented in Table 1 and stratification is presented in Table 2.

Conclusions

Uncontrolled DCD kidneys under normothermic preservation have a rate of postoperative complications comparable to that of DBD kidneys, with no differences in time of onset or severity. We therefore believe that postoperative complications are not an obstacle when it comes to use DCD kidneys as a source of grafts to fight against organ shortage.

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