The Assessment of Cardiovascular Risk in Renal Transplant Recipients

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Abstract

Introduction

The cardiovascular diseases are the most common cause of death in patients with chronic kidney disease (CKD), including patients after kidney transplantation.

Aim

The retrospective analysis of cardiovascular (CV) risk in renal transplant recipients (RTRs).

Methods

The analysis of CV risk was made based on scales: QRISK (assessment of development CV disease), Pol-SCORE (assessment of CV death) during 10 years.

Material

100 RTRs, (M-65/F-35), transplanted in 2007-2009, in the average age 48.4 years were enrolled to the study. Coronary heart disease and diabetes were diagnosed in 7% and 15% of participants, respectively. Coronarography was performed in 38% of patients. Hypertension was diagnosed in 98% of participants, 6% and 2% of them experienced myocardial infarction and stroke, respectively.

Results

The highest risk of the CV endpoint according to the QRISK and Pol-SCORE scales was in 41%, and 41% patients, respectively. After 5 years of follow up total of 13 CV events (myocardial infarction, stroke) in 11 patients were observed. Among these patients, the highest risk of endpoint according to QRISK and Pol-SCORE scales was in 36% and 45% of patients, respectively.

Conclusions

1. In 41% of RTRs a significant risk of CV endpoint according to QRISK and Pol-SCORE scales were assessed.2. After 5 years of follow up in RTRs, CV events occurred in 11% of patients. 3. The Pol-SCORE scale seem to be more useful tool for assessment of CV risk in RTRs in Poland.

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