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To evaluate whether cerclage wire or a lateral plate increases the peak-torque load to failure, compared to femora without adjunctive fixation, in femora implanted with Zurich Cementless stems.In vitro biomechanical study.Paired femora from adult dogs (n = 24) weighing 28–35 kg.Pairs of femora were implanted with a stem and randomly assigned to 2 treatment groups: cerclage or plate. Within each pair, either 3 loop cerclage wires or a laterally applied 12-hole Advanced Locking Plate System 10-mm plate (ALPS 10) were implanted in a femur, whereas the contralateral femur acted as control with no adjunctive fixation. After application of a static axial load each specimen was loaded to failure in torsion. Peak torque load at failure was compared between femora with each adjunctive fixation and the control using a paired t-test; P < .05 was considered significant.In both treatment groups, femora with adjunctive fixation failed at higher loads compared to the femora without fixation; however, significant difference in peak torque at failure between treated femora and control was found only in the plated group (P < .05). Femora implanted with plates and with cerclage were 13.9% and 7.2% stronger in torsion than the femora without fixation, respectively.Adjunctive fixation with a laterally applied ALPS 10 may aid in the prevention of peri-prosthetic fractures associated with Zurich Cementless medium stems.