About 20 trace elements were analysed in samples from 60 boreholes located in the Upper East and West Regions of Ghana. Findings from the analysis indicated that most trace element concentrations were higher as compared to their concentrations found in natural water systems. The available chemical data of rocks in the area suggest that local bedrock is the dominant source of the trace elements found in goundwater. Aluminium, Fe, Mn, Zn, Sr, and Ba were excessively high in concentration. In comparison with WHO guidelines, all except Al, Fe, Fe and Mn values were below the recommended limits.