Tribute to Eda T. Bloom, PhD
Compiled by Dr. Michael E. Breimer, Transplant News Section Editor, and Transplant News *
A CONSENSUS DOCUMENT BASED ON THE PIG-TO-MAN ISLET TRANSPLANT SUMMIT HELD IN STOCKHOLM, JUNE 4–5, 2007
Opening remarks
What type of islets should be used?
What strain of pig should be used?
Gene-modified pigs
The rationale and practical issues for the maintenance of clean herds for clinical islet xenotransplantation
Isolation and assessment of islet quality
The instant blood-mediated inflammatory reaction in xenogeneic islet transplantation
Extrahepatic transplant sites for islet xenotransplantation
Selection of candidates for islet xenotransplantation
Islet xenotransplantation
Immunosuppressive protocols for pig-to-human islet transplantation
Co-transplantation of human and pig islets
Moving towards clinical application
Regulatory aspects of pig-to-human islet transplantation
No infection with porcine endogenous retrovirus in recipients of acellular porcine aortic valves
Pig islet xenograft rejection in a mouse model with an established human immune system
Characterization of porcine UL16-binding protein 1 endothelial cell surface expression
Xenotransplantation literature update November–December, 2007
Manuscript reviewers, 2007