α1,3Galactosyltransferase knockout pigs produce the natural anti-Gal antibody and simulate the evolutionary appearance of this antibody in primates
N -linked glycan profiling of GGTA1/CMAH knockout pigs identifies new potential carbohydrate xenoantigens
Histopathologic insights into the mechanism of anti-non-Gal antibody-mediated pig cardiac xenograft rejection
Xenotransplantation literature update, July–August 2013
iABO KT in Japan: The present status of ABO-incompatible kidney transplantation in Japan – Lessons from more than 2,500 transplants during 24 years
iABO KT in Japan: Simultaneous pancreas and kidney transplantation from ABO-incompatible living donors in Japan – Six consecutive clinical trials in a single institution
iABO KT in Japan: Impact of rituximab desensitization on blood-type-incompatible living donor liver transplantation in adults: A Japaese multicenter study
Desensitization in kidney transplantation at Cincinnati College of Medicine
Desensitization in kidney transplantation at Cedars-Sinai Medical Center
Desensitization in living donor kidney transplantation in South Korea
Desensitization protocol in HLA cross match positive kidney transplant patients in Japan
Peripheral B cell culture for assessment of immune response to ABO blood type carbohydrate antigens
Comparative study on donor ABO antigen expression levels in red blood cells, platelets and graft endothelial cells
Blood group antigen-targeting peptide suppresses blood clotting and immunoglobulin deposition in renal glomerular capillaries after ABO-incompatible blood reperfusion
Blood group-A mice as a model for ABO-incompatible (ABOi) heart transplantation (HTx)
Implication of complement regulatory proteins and AMP-regulated kinase for graft accommodation
The GABO i R-Registry will help to improve the health and risk stratification in ABO incompatible transplanted patients – Gaboir is the abbreviation for German ABO incompatible renal transplant registry
A single low dose rituximab ensures excellent outcome of ABO incompatible kidney transplantation
ABO antibodies can give rise to positive flow cytometric T-lymphocyte crossmatch tests in the absence of HLA antibodies
Comparative study of ABO-incompatible kidney transplants using rituximab without splenectomy and ABO-compatible kidney transplants
ABO incompatible kidney transplantation without plasmapheresis or plasma exchange
Examination of ABO-incompatible kidney transplantation without methods of removing anti-ABO antibodies pretransplant
Low doses of everolimus plus tacrolimus for ABO-incompatible kidney-transplant recipients
Outcomes of ABO-incompatible living-donor kidney transplantation
The impact of Fcγ receptor polymorphisms on the outcome of ABO-incompatible living donor liver transplantation
The feasibility of preoperative desensitization in recipients with high T lymphocyte cross-match titer in adult living donor liver transplantation
Expression of ABO (ABH) histo-blood group antigens in the normal lungs and chimerism in the explanted lungs after ABO incompatible hematopoietic stem cell transplantation
Long-term evaluation of ABO antibodies after allogeneic ABO incompatible hematopoietic stem cell transplantation
Examination of anti-donor blood-type antibodies in cases of ABO incompatible kidney transplantation from living donors – 1
The different sensitivity of B cells responding to carbohydrate and HLA antigens to immunosuppressants
Accommodation: Lessen from clinical cases
Opening aim/scope of the joint congress
Modification of B-cells in alloimmunity
Strategy to overcome Non-Gal Nab in xenotransplantation
Our current strategies to address the remaining obstacles in life-supporting renal xenografts
Preclinical life-supporting lung xenotransplantation – Where do we stand?
What progress has been made in pig-to-nonhuman primate transplantation models during the past 15 years? A retrospective review of the literature
Combined CD40-CD154/CD28-B7 costimulation blockade successfully replaces anti-CD154mAb in preventing a T cell response to genetically-engineered pig artery patch transplants in baboons
Effect of systemic Anti-154 (CD40L) antibody on clinical outcomes of full-thickness porcine corneal graft in pig-to-rhesus corneal transplantation model
In vitro and in vivo testing of an anti-CD40mAb clone, 2C10, in xenotransplantation
Life supporting pig-to-primate xenotransplantation model using transgenic GalT KO pigs: The Padua experience
Porcine CMV may be the causative agent of porcine kidney rejection in GalT-KO pig to nonhuman primate preclinical xenotransplantation
Detection of cytomegalovirus-related gastrointestinal tract lesions in a series of 45 xenotransplanted primates
Advances in a life-supporting xenogenic lung transplant model
Over 9 months graft survival of GTKO.hCD46tg.hTMtg pig heterotopic heart xenograft in Anti CD40 (2C10) treated baboon
The heterotopic thoracic cardiac xenotransplantation model (pig-to-baboon) with and without an additional myelodepressive regime
Expression of human thrombomodulin delays the development of thrombotic microangiopathy and consumptive coagulopathy after pig-to-baboon heart transplantation
Bortezomib does not significantly reduce anti-nonGal antibody production in HLA-sensitized patients
Human thrombomodulin regulates complement activation as well as coagulation in xenoimmune response
Are there advantages in the use of specific-pathogen-free baboons in pig organ transplantation models?
Effective induction of graft accommodation by controlling signaling pathway
Correlation between anti-pig antibody levels in humans and geographic location during childhood: Implications for clinical xenotransplantation
ECDI-fixed donor SPs infusion based combination treatment for induction of tolerance in porcine to mouse islet xenotransplant model
Successful isolation of viable neonatal porcine islets from 24 hours cold-stored pancreata
Development of a clinically relevant protocol for the isolation of neonatal porcine islets
The anti-oxidant effects of Cyanidin-3-O-glucoside (C3G) and Manganese (III) meso-tetrakis (N-ethylpyridinium-2-yl) porphyrin (MnTE-2-PyP) on neonatal pig islets
Extremely high islet yield enables one-donor-one recipient intraportal islet transplantation with enough islet mass in pig-to-non-human primate model
Transgenic tilapia with islets secreting humanized insulin – Free to a good home
Improving porcine islet yield with new class 1, class 2 collagenases (Mammalian tissue free) in combination with dispase
Optimization of a porcine islet isolation and purification procedure that utilizes recombinant collagenase
Defective patterns of porcine endogenous retrovirus in SNU miniature pigs can be used as a discrimination marker
No apparent transmission of HEV via kidney xenotransplantation in a pig to primate model, but potential reactivation of pre-existing HEV infection
The attitude toward xenocorneal transplantation in wait-listed patients for corneal transplantation in Korea
Attitude toward xenotransplantation among secondary school teachers in the southeast of Spain
The impact of the zoonotic outbreak due to the swine influenza a (H1N1) virus on veterinary students' perception of xenotransplantation
The therapeutic role of monocytes chemoattractant protein-1 in a renal tissue engineering strategy for diabetic patients
Anti-α-Gal antigen/antibody may not be important in the failure of bioprosthetic heart valves
Simultaneous over-expression of graft protective hHO-1, hCD73 and hCD39: Effects against cell cytotoxicity and cell death induced by the inflammatory cytokine TNF-α in an in vitro model
A tissue-engineered subcutaneous pancreatic cancer model for antitumor drug evaluation
Production of transgenic pigs with down-regulation of SLA Class II on a GTKO/CD46 genetic background
Density, morphology, and in vitro proliferative capacity of porcine corneal endothelial cells: Relevance to clinical corneal xenotransplantation
Xenotransplantation resources available through the National Swine Resource and Research Center
Optimization of cytotoxicity assay by real-time, impedance-based cell analysis
Bone marrow and haemathological evaluation of 62 xenografted cynomolgus monkeys
Plasma free triiodothyronine (fT3) levels in baboons undergoing pig organ transplantation; relevance to early recovery of organ function
Remote ischemic preconditioning (RIPC) protocol for kidney xenotransplantation in swine
RNase: A new player in (xeno)transplantation?
Does soluble CD154 (CD40 ligand) promote elicited anti-pig IgG antibodies in xenograft recipients?
Intra-bone bone marrow transplantation achieves longer peripheral macrochimerism and prolongs xeno-kidney graft survival in a pig-to-baboon xeno-transplantation model
Initial evidence for functional immune modulation in primate recipients of porcine skin grafts following conditioning with human CD47 transgeneic pig hematopoietic stem cells
Xenograft tolerance and immune functions of human T cells developing in pig thymus xenografts in humanized mice
Long-term comparative study on the engraftment of human hematopoietic stem cells in sheep after xenogeneic in utero transplantation
Low and tapering dose of anti CD40 (2C10 or 3A8) for 8-week duration fails to extend GTKO.hCD46Tg pig to baboon cardiac xenograft survival beyond 5 months
Pig to baboon heterotopic cardiac xenotransplantation: Potential role of baboon CD4+ CD25Hi FOxP3+ T regulatory cells in long-term graft survival
Sensitization to nonGal antigens is significantly reduced in baboons with artery patch grafts from GTKO pigs transgenic for a mutant human MHC class II transactivator (CIITA)
Porcine adipose-derived MSC might have a risk of enhancing T cell response, unlike human, mouse or rat MSC
Do pig mesenchymal stromal cells regulate human T cell responses to pig antigens through modulation of CD69 expression?
Poly I:C-activated monocytic suppressor cells suppress xenogenic cytotoxicity via IDO-dependent mechanisms
Novel immumodulatory effects of extracorporeal photopheresis after heart transplantation
Expression of human coagulation-regulatory proteins on pig vascular endothelial cells reduces in vitro human platelet aggregation
Activated protein C modulates the thrombotic phenotype of human endothelial protein C receptor transgenic porcine endothelium
In vitro assessment of the compatibility of thrombomodulin and endothelial protein C receptor in the pig-to-human setting
Endothelial-specific expression of biological active human thrombomodulin in single-transgenic pigs and pigs with multiple genetic modifications
Control of procoagulant state using anticoagulant factor thrombomodulin in xenotransplantation
The application of chimerism, small molecule inhibitors, and anti-idiotypic single chain antibodies to inhibit anti-non-gal xenoantibody responses
N-linked glycan profiling of GGTA1/CMAH knockout pigs identifies new potential carbohydrate xenoantigens
Cloning and expression of the porcine beta 1,4-N-acetylgalactosaminyl transferase which synthesizes a new xenoreactive antigen
N-glycolylneuraminic acid is strongly expressed in the pig cornea: Relevance to corneal xenotransplantation
Development of anti-pig antibodies and characterization of B cell phenotype following wild-type pig-to-monkey corneal xenotransplantation
Long-term IgG response to porcine Neu5Gc-antigens in burn patients treated with porcine skin xenografts
Coagulative profile in life supporting gal KO pig-to-primate kidney xenotransplantation
Manual adult porcine islet isolation technique and optimal condition for adult pig islets
Ex vivo expanded Tregs suppress the baboon anti-pig T and B cell response
Pathologic characteristics of transplanted GalTKO pig kidney xenografts in baboons
Desensitization in living donor kidney transplantation in South Korea
Bone marrow xenotransplantation
Pig islet transplantation with costimulation blockade
DC suppression and tolerance to xenoislets with MD3
Advantages of xenoislet over alloislet transplantation
Pathogen recognition receptors and innate immunity
Heart – Current progress in xenogeneic heart transplantation
Generation of organs by interspecific blastocyte injection of iPS cells
Induction of species-specific tolerance to human islet xenografts by anti-CD45RB
The adult porcine islets preparation contained several glycans that were not detected in human islets
Deciphering the mechanistic pathways of the instant blood mediated inflammatory reaction against porcine neonatal islet cells
Purified human factor H reduces early loss of islet graft in non-human primates with intraportal porcine islet xenotransplantation
Genetically-engineered pig islets modulate early loss after transplantation into diabetic monkeys
Neonatal and adult pig islets activate the human coagulation and complement systems equally in an in vitro model of IBMIR
Porcine neonatal islet cell clusters that express human CD55-CD59 with Gal KO prevent thrombosis in a pre-clinical baboon study
Streptozotocin-associated lymphopenia in monkeys: relevance to islet xenotransplantation
Alginate-PEG biomaterial for cell microencapsulation and xenotransplantation
The survival of free and encapsulated islets xenograft transplanted in the mouse bone marrow
Four-dimensional in-vitro modeling of xenogeneic thrombosis under shear flow: A novel technique
A pig-to-mouse coronary artery transplantation model for investigating the pathogenicity of Gal and non-Gal reactive antibody
Do genetically-engineered pig-to-baboon artery patch transplants reflect the coagulation dysregulation/inflammation (CD/I) seen after pig-to-baboon heart transplants?
Targeting vWF and GPIb pathways to attenuate thrombocytopenia in a xenogenic pig-to-baboon liver perfusion model
Upregulation of inflammation and coagulation genes is associated with GalTKO.hCD46 xenogenic lung injury
Thrombin generation and platelet activation in a xenogenic lung perfusion model determine survival of GalTKO.hCD46 transgenic lungs
Human EPCR expression in GalTKO.hCD46 lungs extends survival time and lowers PVR in a xenogenic lung perfusion model
Attenuation of hyperacute dysfunction and microangiopathy by the treatment of carbon monoxide in GalT-KO pulmonary xenotransplantation
Ex-vivo perfusion of multiple genetically modified pig hearts
Elimination of xenoreactive antibodies did not affect xenogenic activation of coagulation in xenoperfused porcine kidneys
Use of echocardiography to assess heterotopic cardiac xenograft function and clot reduction therapeutic intervention in a transgenic pig to baboon model
ASGR1 expressed by porcine aortic endothelial cells mediates human platelet phagocytosis in in vitro as well as during ex vivo pig-to-human porcine forelimb xenoperfusion
Phagocytic cellular responses in xenotransplantation
Xenograft rejection of bioprosthetic heart valves
Genetic engineering of source pigs for xenotransplantation: Progress and prospects
Genetically engineered donor pigs with improved pancreatic islets
Tg pigs – recent progress: Multiple Tg+GalTKO
Decellularized xenogeneic tissues as a novel biomaterial
Update on assays for detection of PERVs
Expression of recipient CD47 on rat insulinoma cell xenografts prevents macrophage-mediated rejection through SIRPα inhibitory signaling in mice
Engraftment and peripheral persistence of human CD47 transgenic porcine progenitor cells in CHEF-NSG mice
Regulation of macrophage-mediated xenocytotoxicity by overexpression of alpha 2,6-sialyltransferase in swine endothelial cells
The suppression of inflammatory macrophage-mediated cytotoxicity and proinflammatory cytokine production by transgenic expression of HLA-E
Reduction of human NK cell recruitment by transgenic HLA-E expression in a model of ex vivo xenogeneic pig-limb perfusion
Human tolerogenic dendritic cells inhibit xenogeneic NK cell responses
Activation of the lectin pathway of complement in pig-to-human xenotransplantation models
Safety of xenotransplantation: How to screen the donor pig and the recipient
Restriction of PERV subtypes by ZFP809 and TRIM28
Porcine CMV infection is associated with early rejection of kidney grafts in a pig-to-baboon xenotransplantation model
Lymphocryptovirus-associated post-transplant lymphoproliferative disorders and viral transcript expression in Cynomolgus macaque recipients of porcine neuronal precursors
hCTLA4-Ig transgene expression in keratocytes improves survival of xenogeneic cornea graft in a transgenic Pig to Non Human Primate lamellar keratoplasty model
Systemic immunosuppression plus local production of CTLA4-Ig to control rejection of transgenic pig neuroblasts in non-human primates
Transplantation of encapsulated neonatal porcine choroid plexus cells for Parkinson's disease
Ex vivo xenoperfusion of (hCD46 & HLA-E)-double transgenic porcine forelimbs with whole, heparinized human blood: Study of early immunological responses
In vitro human immune response to corneal endothelial cells from α1,3-galactosyltransferase gene-knockout pigs transgenic for hCD46 and dominant-negative class II transactivator-knockdown
The GalT-KO/FucT-TG pig does not appear to have an advantage over the GalT-KO pig with respect to glycolipid reactivity with human serum antibodies
Ubiquitous CD39 expression is associated with reduced birth weight and viability of cloned transgenic piglets
Generation of chimeric pigs as donors for xenotransplantation: Performance of a technique for percutaneous ecoguided stem cells in utero transplantation
Production and characterization of soluble human TNFRI-Fc and human HO-1 double transgenic pigs by using the F2A peptide
Single-step two porcine gene editing mediated by CRISPR/Cas9 system and efficient selection of genetically modified porcine cells
Generation of CMAH−/− piglets on GAL−/− genetic background
Targeting of a porcine EGFP line mediated by ZFNs to establish cloned Puromycin resistant primary cell lines suitable for Cre-mediated RMCE
Application of blastocyst complementation to development of genetically modified pigs for xenotransplantation
Factors influencing engraftment of monkey embryonic stem cells in sheep after xenogeneic in utero transplantation
In vivo generation of exogenic pancreas in apancreatic cloned pigs via blastocyst complementation
Development of novel combined anticalcification protocols including immunologic modification for prolonged durability of cardiac xenograft: Preclinical study using large-animal longterm circulatory models
In-vivo efficacy for treatment with decellularization, alpha-galactosidase, space filler, organic solvent and detoxification of glutaraldehyde-fixed cardiac xenograft using alpha1,3-galactosyltransferase knock-out mouse implantation model
A comparison of three methods of decellularization of porcine corneas to reduce immunogenicity following anterior lamellar keratoplasty
Do bioprosthetic heart valves undergo xenograft rejection in patients?
Encapsulated mesenchymal stem cells xenotransplanted in mice produce anti-inflammatory cytokines and delay liver fibrosis
Effect of Rho/Rho kinase inhibitor, Y-27632, on inflammation in cultured porcine corneal endothelial cells: relevance to corneal xenotransplantation
Ethical and regulatory guidelines in clinical trials of xeno-corneal transplantation in Korea: The Korean Xenocorneal transplantation Consensus statement
Mortality after bone marrow transplantation in an Asian population
Examination of anti-donor blood type antibodies in cases of ABO incompatible kidney transplantion from living donors - 2
Monitoring of graft function and rejection in the heterotopic thoracic pig-to-baboon cardiac xenotransplantation model
Donor specific hyporesponsiveness in kidney transplantation using adoptive transfer of ex vivo induced tolerogenic cells
The structures of N-glycans of neonatal porcine islet-like cell clusters
C1q-fixing human leukocyte antigen assay for chronic antibody-mediated rejection in renal transplant recipients
Optimal masking of CD25 turnover by antibody preserves membrane CD25 stability and enhances the purification yield of CD4+CD25+CD127-Treg cells in Rhesus monkey
Development of TG cloned pigs with multiple genes associated with human immune rejection response for xenotransplantation
Generation of triple transgenic hHO-1/GGTA-1—/—/hCD55 pigs using zinc-finger nucleases and sleeping beauty transposition
Immunophenotyping and monitoring of immune cells in rhesus monkeys: Application to pig-to-monkey xenotransplantation
A Salutary effect of calorie restriction on the fasting glucose levels after porcine islet transplantation into the diabetic monkeys
Telemetry, echocardiography and manual palpation of heterotopic cardiac xenograft together improves the measurement accuracy of graft contractility
A modified technique for heterotopic heart xenotransplantation from mouse to rat
Intermediate xeno host rescues small for size liver graft syndrome in rodent
Expression analysis of target genes using a bi-cistronic T2A expression system
Simultaneous expression of novel combinations of graft protective human genes in porcine endothelial cells
Detecting the presence of hTM in lung tissue of GalTKO.hCD46.hTM transgenic pigs
Systemic and renal response of Gal-/- pigs to human angiotensin II
Production of pigs with increased xeno-relevant transgene expression
Generation of transgenic pigs carrying an siRNA vector directed against Tissue Factor expression
Germline transmission of transgenic boars carrying hDAF/hHO-1 genes
Growth performance and blood clinical chemistry of transgenic pigs with hDAF/hHO-1 dual exo-genes
The Characterization of expression of exogenes and pathological observation in hDAF/hHO-1 dual transgenic pigs
Development of recellularized three-dimensional scaffold using porcine liver
A tissue engineered renovascular graft composed of proteins, polymers, smooth muscle and endothelial cells for renal artery stenosis
Microencapsulation of porcine pancreatic islets and separation of empty alginate capsules
Citotoxic effect of ultrasound contrast used for in utero stem cells implant, assessed by real time impedace profile analysis
Irish citizens resident in the south east of Spain and their attitude toward xenotransplantation
Attitude toward xenotransplantation among adolescents in the southeast of Spain
Decellularized porcine liver as an three dimensional tool for organ specific differentiation from mouse embryonic stem cells
Porcine liver derived extracellular matrix extract as a tissue specific coating for cell culture and hepatic differentiation
Human HO-1 and sTNF-aR-Fc in porcine islets prolongs islet xenograft survival in humanized mice
Between centre and periphery: Medi(c)ating the risks of infectious diseases in islet xenotransplantation